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Pirfenidone (S-7701)
Cat. No.:
OB0225WX-2539
Appearance:
Solid
Purity:
≥99%
Identity:
Confirmed by NMR, and HPLC.
Size:
Add to basket
Product Overview
Description:
Pirfenidone (S-7701) is a small molecule that suppresses the production of TGF-beta, TNF-alpha, and IL-1-beta while reducing the levels of chemokines such as CCL2 and CCL12.
Synonym:
AMR-69; 53179-13-8; 5-methyl-1-phenylpyridin-2(1H)-one; Esbriet; Deskar; Pirespa; AMR-69; 5-Methyl-1-phenyl-2-(1H)-pyridone; Pirfenidona; Pirfenidonum; 5-methyl-1-phenyl-2(1H)-pyridinone; 2(1H)-Pyridinone, 5-methyl-1-phenyl-; AMR 69; 5-methyl-1-phenylpyridin-2-one; 5-Methyl-1-phenyl-2(1H)-pyridone; 5-Methyl-1-phenyl-1H-pyridin-2-one; 2(1H)-Pyridone, 5-methyl-1-phenyl-; 5-Methyl-1-phenyl-2-pyridone; 5-methyl-1-phenyl-2-pyridinone
CAS No.:
53179-13-8
Compound CID:
40632
Formula:
C12H11N
Formula Weight:
185.22
Specification
Stability:
3 years in powder form.
Storage:
Storage at -20°C.
Applications:
Pirfenidone (S-7701) is utilized in fibrotic disease research to examine the inhibition of collagen synthesis and the modulation of TGF-beta signaling pathways in lung and tissue remodeling models.
Library Information
Target:
TGF-β; TNF-α; CCL2
Receptor:
TGF-β; TNF-α; CCL2
Pathways:
TGF-beta/Smad
Plate Number:
L6700-05
Empty Location:
a1-h1; a12-h12
Container:
96-well plate
Formulation:
10mM DMSO
DMSO Max Solubility:
37 mg/mL; 199.76 mM
Ethanol Max Solubility:
37 mg/mL
ALogP:
1.905
HBA_Count:
1
HBD_Count:
0
Rotatable Bond:
1
