LDN-193189 2HCl

Cat. No.: OB0225WX-2810

Appearance: Solid

Purity: ≥99%

Identity: Confirmed by NMR, and HPLC.

Size:

INQUIRY Datasheet MSDS

Add to basket

Product Overview

Description: LDN-193189 is a selective BMP signaling antagonist that inhibits ALK1, ALK2, ALK3, and ALK6 with IC50 values ranging from 0.8 nM to 16.7 nM, exhibiting 200-fold selectivity over TGF-beta pathways.

Synonym: DM-3189 2HCl; 1435934-00-1; LDN 193189 dihydrochloride; LDN 193189 hydrochloride; LDN-193189 dihydrochloride; LDN-193189 (dihydrochloride); 4-[6-(4-piperazin-1-ylphenyl)pyrazolo[1,5-a]pyrimidin-3-yl]quinoline;dihydrochloride; 4-[6-[4-(1-Piperazinyl)phenyl]pyrazolo[1,5-a]pyrimidin-3-yl]quinoline hydrochloride; 4-(6-(4-(piperazin-1-yl)phenyl)pyrazolo[1,5-a]pyrimidin-3-yl)quinoline dihydrochloride

CAS No.: 1435934-00-1

Compound CID: 91900717

Formula: C₂₅H₂₄Cl₂N₆

Formula Weight: 479.4

Specification

Stability: 3 years in powder form.

Storage: Storage at -20°C.

Applications: LDN-193189 2HCl is applied in developmental biology and regenerative medicine research as a potent and selective ALK2 and ALK3 inhibitor to study the regulation of BMP signaling and its role in tissue differentiation.