Overview

Adipose tissue is a connective tissue that extends throughout the body and is found under the skin, between internal organs, and so on. It performs various functions such as energy storage and release, maintaining energy balance, regulating glucose and cholesterol, and maintaining insulin sensitivity. It has been found that dysfunctional adipose tissue may lead to various metabolic disorders, such as insulin resistance leading to diabetes, and dysfunctional hunger and satiety signaling leading to obesity. Protheragen offers a one-stop adipose tissue cell functional analysis service to help better explore the role of adipose tissue in health and disease.

Precise Insights into Adipose Tissue Cell Function

Through detailed testing of adipose tissue cells, we provide insight into the functional state of adipose tissue and its role in studying Obesity Pathobiology (e.g., energy storage, metabolic regulation, and hormone secretion). The cell types tested include but are not limited to adipocyte function (white adipocytes, brown adipocytes) and immune cell function, and the specific tests include the following:

Observation of Adipocyte Cell Structure

Observing adipocyte cell structure plays a pivotal role in understanding adipocyte function. Our analysis encompasses adipocyte hypertrophy and perivascular localization in preadipocytes, cold-induced lipid droplet formation, and mitochondrial reorganization in brown adipocytes.

Energy Storage Analysis

Adipose tissue serves as the primary energy depot in the human body, storing energy in the form of triglycerides (TAGs). The functionality of adipocytes in storing and releasing energy is evaluated by assessing the levels of triglycerides and fatty acids.

Adipose Metabolism Testing

Adipose metabolism disorders constitute a diverse spectrum of metabolic conditions, typically marked by a compromised capacity to form functional adipose tissue. Our adipose metabolism assays meticulously evaluate the role and status of adipose tissue in metabolic processes, offering robust support for obesity research endeavors and therapeutic development initiatives.

Single-Cell Transcriptomic Analysis

Leveraging advanced methodologies, including single-cell transcriptomic analysis, we delve into the realm of functional genomics and metabolic impacts. Single-cell transcriptomic analysis stands as a potent tool, delivering transcriptomic data with unparalleled precision at the single-cell level. This enables the elucidation of biological attributes and functional disparities among diverse cell types within adipose tissue. Through this analysis, we meticulously construct a cellular atlas of adipose tissue, furnishing crucial insights into its structure and function.

Hormone and Cytokine Analysis

Hormones and cytokines secreted by adipocytes, such as lipocalin and leptin, are assayed to assess their role in regulating energy metabolism, insulin sensitivity, and immune response.

Applicable Sample Types

This service is available for the following sample types. Strict project standards ensure our scientific accuracy and reliability in experimental protocol design, sample preparation, and data analysis.

• Adipose tissue samples from different sources (mice, rats, rabbits, pigs, etc.)
• Other types of samples

Anti-Obesity Therapy Development

In addition, we also provide anti-obesity therapeutic development services targeting various targets and one-stop therapeutic preclinical research services.

Workflow

Adipose tissue cell function analysis services support a variety of applications from basic research to the development of targeted therapies for obesity. The combined use of transcriptomes, proteomes, and metabolomes provides a wide range of information for adipose tissue cell function analysis.

Applications

• Adipose tissue cell function analysis provides useful information for researchers to understand in detail their specific functions and roles in health and obesity.
• Adipose tissue cell function analysis helps to understand the various roles of adipose tissue in obesity, insulin resistance, and other metabolic diseases, providing valuable data for developing therapeutic strategies.
• Adipose tissue cell function analysis helps to design effective weight management measures through effective nutritional planning to achieve weight loss and improved metabolism.

Advantages

• We combine single-cell transcriptome analysis, proteomics, and metabolomics to describe in detail the behavior and specific functions of adipose tissue cells.
• The insight into adipose tissue cell function provides valuable information for understanding conditions associated with obesity and other metabolic disorders.
• We provide a variety of resources for researchers studying obesity and facilitate research into targeted obesity therapies.

Publication Data

Frequently Asked Questions

1. What is the purpose of the adipose tissue cell function analysis service?

   This service aims to provide a comprehensive understanding of the physiological and functional diversity of adipose tissue, in particular the role of adipose tissue in energy storage, metabolism, and hormone regulation.

2. What types of cells are analyzed by this service?

   This service evaluates white adipocytes, brown adipocytes, and immune cells. The analysis of these cellular functions is essential for obesity research.

3. What methods are used in the analysis?

   Advanced methods such as single-cell transcriptome analysis are used to characterize different cells within adipose tissue and to study their specific roles in health and obesity.

At Protheragen, our detailed analysis of adipose tissue function provides comprehensive information and reliable support for a detailed understanding of the mechanisms that develop and drive obesity. Please feel free to contact us to inquire about adipose tissue cell function analysis services to help you with your experiments.

All of our services and products are intended for preclinical research use only and cannot be used to diagnose, treat or manage patients.

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