Inflammatory Cytokine Analysis Service
InquiryOverview of Inflammatory Cytokines
Protheragen is well aware of the severity of obesity and its profound impact on society. Therefore, we have set up the Obesity Biomarker Identification and Analysis Services in Our Services section, aiming to provide strong support for obesity research through advanced scientific and technological means.
Inflammatory cytokines, as important biomarkers in obesity and related diseases, are of great significance for understanding obesity-induced immune disorders, inflammatory responses, and their pathological mechanisms. We provide new ideas and strategies for the treatment of obesity by deeply analyzing these cytokines.
Elevate Your Obesity Studies with Our Inflammatory Cytokine Analysis
Inflammatory Cytokines in Obesity
Inflammatory cytokines, including tumor necrosis factor-alpha (TNF-α), interleukin-6 (IL-6), and C-reactive protein (CRP), play a pivotal role in the metabolic disruptions observed in obesity. These cytokines are primarily produced by adipose tissue and contribute to the chronic low-grade inflammation characteristic of obesity. Elevated levels of these cytokines are linked with insulin resistance, increased lipolysis, and other metabolic anomalies.
Analysis of Inflammatory Cytokines
Our analysis of inflammatory cytokines involves an array of state-of-the-art techniques designed to elucidate their levels and functional roles in obesity. Our customized approach ensures that each analysis adapts to the specific needs of the study or clinical requirement, involving several advanced steps:
- Sample Collection and Preparation: We ensure meticulous handling of biological samples to preserve the integrity of cytokines, employing standardized protocols to minimize variability.
- Qualitative and Quantitative Analysis: Utilizing technologies such as enzyme-linked immunosorbent assay (ELISA), Luminex assays, and mass spectrometry, we precisely quantify cytokine concentrations. Flow cytometry is employed to assess cytokine profiles in various immune cell populations, providing insights into the cellular origins of inflammatory responses.
- Data Interpretation and Custom Reporting: Comprehensive data analysis elucidates the role of cytokines in patient-specific or population-wide metabolic dysregulation, offering clear interpretations aligned with clinical or research objectives. Customized reports are crafted to cater to specific insights necessary for advancing hypothesis-driven research or therapeutic strategies.
- Customized Service: We understand that each client's specific situation and research needs are unique, so we provide customized Inflammatory cytokine analysis services. Clients select specific cytokines for testing based on their needs or ask us to conduct a more in-depth analysis and interpretation of the test results. We also provide consulting and collaboration services to help clients design research plans, interpret research results, and jointly explore new strategies for the treatment of obesity.
Workflow
Applications of Inflammatory Cytokines
- Uncovering the metabolic mechanisms caused by obesity: Inflammatory cytokines can be used to study the inflammatory response of adipose tissue in obese individuals. These cytokines play a key role in the pathogenesis of metabolic diseases such as adipose tissue remodeling, insulin resistance, and hyperlipidemia.
- Evaluating the efficacy of obesity treatment drugs: In the process of drug development, inflammatory cytokines can be used as biomarkers to evaluate the efficacy of obesity treatment drugs.
- Studying the relationship between obesity and chronic inflammation: Inflammatory cytokines can be used to study the close connection between obesity and chronic inflammation, and explore how obesity affects the health of the body by activating inflammatory pathways.
Advantages
- Advanced technology platform: We have an advanced and efficient technology platform that accurately and quickly detects and analyzes the level of inflammatory cytokines.
- Rich experience: We have rich experience in inflammatory cytokines analysis and provide clients with professional consultation and solutions.
- Professional technical support: We provide clients with professional technical support and after-sales service.
Anti-Obesity Therapy Development
We recognize the pivotal role of our inflammatory cytokine analysis service in advancing anti-obesity therapy development. By meticulously analyzing inflammatory cytokines as biomarkers, we provide crucial insights into the mechanisms underlying obesity-related inflammation, guiding our efforts in Anti-Obesity Small Molecule Drug Development, Anti-Obesity Cell Therapy Development, and Anti-Obesity Tissue Engineering Therapy Development.
Publication
Published: 2016
Journal: Disease Markers
IF: 3.4
Results: The article explores the role of inflammatory cytokines as biomarkers in obesity-related diseases, particularly in the context of chronic periodontitis. It highlights that while C-reactive protein levels may not differ significantly between obese and non-obese individuals with periodontitis, tumor necrosis factor-alpha is elevated in obese patients. The review suggests that localized periodontal inflammation might more significantly affect proinflammatory biomarker levels in gingival crevicular fluid than systemic obesity. However, the relationship between chronic periodontitis, obesity, and elevated biomarkers remains complex and not fully understood.
Fig.1 PRISMA flow diagram for studies retrieved through the searching and selection process. (Akram, et al., 2016)
Frequently Asked Questions
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What is inflammatory cytokine profiling, and how can it help me?
Inflammatory cytokine profiling is a method of assessing the state of inflammation in the body by detecting and analyzing the levels of inflammatory cytokines in the blood or other biological samples. These cytokines are signaling molecules released by the immune system in response to infection, injury, or disease. This analysis can help identify inflammatory processes associated with obesity, diabetes, cardiovascular disease, autoimmune diseases, and more.
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What cytokines are included in your inflammatory cytokine profiling service?
Our inflammatory cytokine profiling service covers a variety of key inflammatory cytokines, including but not limited to interleukin-1 (IL-1), interleukin-6 (IL-6), interleukin-8 (IL-8), tumor necrosis factor-α (TNF-α), and C-reactive protein (CRP). These cytokines play an important role in a variety of inflammatory diseases and are often used as biomarkers of disease activity and treatment efficacy. We customize the assay to include the specific cytokines of interest based on your specific needs.
At Protheragen, our inflammatory cytokine analysis service provides strong support for the research of obesity, helps clients better understand the immune disorders and inflammatory responses caused by obesity, and provides a scientific basis for the development of new treatment strategies. Please feel free to contact us for more details if you are interested in our inflammatory cytokine analysis services!
Reference
- Akram, Z.; et al. Cytokine profile in chronic periodontitis patients with and without obesity: a systematic review and meta‐analysis. Disease markers. 2016, 1: 4801418. (CC BY 4.0)
All of our services and products are intended for preclinical research use only and cannot be used to diagnose, treat or manage patients.