Online Inquiry

Please note that we are not a pharmacy or clinic, so we are unable to see patients and do not offer diagnostic and treatment services for individuals.

Metabolic Enzymes/Proteases

Inquiry

Overview

Fig.1 Phospholipase D structure.Fig.1 Structure of phospholipase D. (Wang, et al., 2021)

Obesity, a complex metabolic disease, occurs through mechanisms involving dysregulation of energy balance and abnormal accumulation of adipose tissue. In this process, metabolic enzymes and proteases play a key role as key molecules that catalyze biochemical reactions. Protheragen focuses on providing diverse, high-quality metabolic enzymes and protease products for research in the field of obesity.

  • Metabolic enzymes are extensively involved in the metabolic processes of fats, carbohydrates, and proteins, regulating energy production, storage, and utilization.
  • Proteases are mainly responsible for the hydrolysis and degradation of proteins, which have a significant impact on the maintenance of amino acid balance, muscle mass, and appetite regulation in the body.

Specialized Suppliers of Metabolic Enzymes/Proteases

An in-depth study of the mechanism of metabolic enzymes and proteases in obesity is of great significance in unraveling the pathophysiological process of obesity and drug development. Our company offers enzyme products derived from a wide range of organisms, including plants, animals, bacteria, and fungi, covering different enzyme species and properties.

Key Metabolic Pathway Enzymes


Fig.2 Glucose entrance change.Fig.2 Regulation of glucose entrance through
insulin signaling. (Russo, et al., 2021)

Our company provides a variety of key metabolic pathway enzymes, such as those involved in glycolysis, tricarboxylic acid cycle, fatty acid synthesis and catabolism, and other key metabolic pathways, which help to study the changes in energy metabolism during obesity.

  • Phosphoglycerate kinase from yeast
  • Glycerol-3-phosphate oxidase from Escherichia coli
  • Glycerol 3-phosphate oxidase from Pedio coccus sp.
  • Glycerol 3-phosphate oxidase from Aerococcus viridans
  • Glycerol-3-phosphate oxidase from the microorganism
  • Glycerol kinase from the microorganism
  • Glycerol kinase from Cellulomonas sp.

Proteases


Our company offers a wide range of high-quality tissue-specific and non-specific protease products, which are widely used in a variety of cutting-edge scientific research fields, especially in obesity-related research, and play an irreplaceable role. By utilizing these proteases, we help our clients to explore the complex mechanisms of protein metabolism.

Obesity is closely related to the imbalance of appetite regulation, and proteases are involved in the regulation of multiple appetite-related signaling pathways. Utilizing these proteases, researchers have delved into the molecular mechanisms of appetite regulation, providing new ideas and methods for the treatment of obesity-related diseases.

  • lysosomal histone protease
  • Papain
  • Pepsin
  • Microbial proteases
  • Pancreatin
  • Tryptase

Publication

Technology: Localized proton magnetic resonance spectroscopy, Enzyme-linked immunosorbent assay (ELISA)

Journal: Molecular Medicine

Published: 2019

IF: 6.0

Results: This study investigated the association between plasma concentrations of proteinase 3 (PR3) and neutrophil elastase (NE) in neutrophil serine proteases (NSPs) and non-alcoholic fatty liver disease (NAFLD) and type 2 diabetes (T2D). The findings suggest that PR3 and NE play a role in the inflammatory state of NAFLD and T2D. The imbalance between NSPs and their inhibitor AAT may be an important factor in obesity-related metabolic diseases. Moreover, circulating levels of NSPs have been associated with obesity-related metabolic diseases.

Fig.3 PR3, NE, and AAT plasma concentrations in patients with type 2 diabetes.Fig.2 PR3, NE, and AAT plasma concentrations analysis. (Mirea , et al., 2019)

Applications

  • Metabolic enzymes/proteases can be used to promote fat metabolism and regulate energy balance.
  • Metabolic enzymes/proteases break down proteins into smaller peptides and amino acids to aid digestion.
  • Metabolic enzymes/proteases can be used to study the effects of different dietary components on the activities of metabolic enzymes and proteases, providing a basis for the development of scientific nutritional intervention strategies.

Advantages of Our Products

  • Diversity and specialization: We provide metabolic enzymes and protease products from various sources and with various properties, covering various fields of obesity research to meet the diversified needs of clients.
  • High quality and stability: All products undergo strict quality control processes to ensure a high degree of purity and activity, guaranteeing reliable and reproducible research results.
  • Professional technical support: We have a professional technical team to provide clients with different types of metabolic enzymes/proteases production services.

Frequently Asked Questions

  1. How do I choose the right metabolic enzyme/protease product for my research?

    When selecting a metabolic enzyme/protease product suitable for research, factors such as the specific needs of the experiment, the characteristics of the target protein, and the purity and activity of the product should be considered. It is recommended to communicate with our technical support team for more specific advice.

  2. Do your products support customized service?

    Yes, we offer customization services. Depending on the specific needs of researchers, we provide metabolic enzyme/protease products with different purities, activities, or specific modifications. Moreover, our company provides artificial intelligence (AI)-assisted enzyme design and production services.

Protheragen provides obesity-related metabolic enzymes/proteases products designed for biological research and intended to support scientific research and experimentation. Our products are highly specific and active, and accurately mimic metabolic processes in organisms in experiments. Feel free to contact us for more information.

References

  1. Wang, F.; et al. Crystal structure of a phospholipase D from the plant-associated bacteria Serratia plymuthica strain AS9 reveals a unique arrangement of catalytic pocket. International Journal of Molecular Sciences. 2021; 22(6):3219. (CC BY 4.0)
  2. Mirea, A.M.; et al. Increased proteinase 3 and neutrophil elastase plasma concentrations are associated with non-alcoholic fatty liver disease (NAFLD) and type 2 diabetes. Molecular Medicine. 2019, 25: 1-10. (CC BY 4.0)
  3. Russo, S.; et al. Meta-inflammation and metabolic reprogramming of macrophages in diabetes and obesity: the importance of metabolites. Frontiers in Immunology. 2021, 12: 746151. (CC BY 4.0)
View more

Lipase Products

Source
Type
Subcategory
Phospholipases D from Streptomyces chromofuscus
  • CAS No.: 9001-87-0
  • EC No.: 3.1.4.4
  • Source: Streptomyces chromofuscus
  • Specific Activity:
Phospholipases D from <i>Streptomyces chromofuscus</i>
Phospholipases D from peanut
  • CAS No.: 9001-87-0
  • EC No.: 3.1.4.4
  • Source: Peanut
  • Specific Activity:
Phospholipases D from peanut
Phospholipases D from cabbage
  • CAS No.: 9001-87-0
  • EC No.: 3.1.4.4
  • Source: Cabbage
  • Specific Activity:
Phospholipases D from cabbage
Phosphoglycerate kinase from yeast
  • CAS No.: 9001-83-6
  • EC No.: 2.7.2.3
  • Source: Yeast
  • Specific Activity: 925 U/mg protein
Phosphoglycerate kinase from yeast
Glycerol-3-phosphate oxidase from E. coli
  • CAS No.: 9046-28-0
  • EC No.: 1.1.3.21
  • Source: E. coli
  • Specific Activity: ≥25 U/mg protein
Glycerol-3-phosphate oxidase from <i>E. coli</i>
Glycerol 3-phosphate oxidase from Pedio coccus sp.
  • CAS No.: 9046-28-0
  • EC No.: 1.1.3.21
  • Source: Pedio coccus sp.
  • Specific Activity:
Glycerol 3-phosphate oxidase from <i>Pedio coccus</i> sp.
Glycerol 3-phosphate oxidase from Aerococcus viridans
  • CAS No.: 9046-28-0
  • EC No.: 1.1.3.21
  • Source: Aerococcus viridans
  • Specific Activity:
Glycerol 3-phosphate oxidase from <i>Aerococcus viridans</i>
Glycerol-3-phosphate oxidase from microorganism
  • CAS No.: 9046-28-0
  • EC No.: 1.1.3.21
  • Source: Microorganism
  • Specific Activity:
Glycerol-3-phosphate oxidase from microorganism
Glycerol kinase from microorganism
  • CAS No.: 9030-66-4
  • EC No.: 2.7.1.30
  • Source: Microorganism
  • Specific Activity: ≥180 U/mg protein
Glycerol kinase from microorganism
Glycerol kinase from Flavobacterium meningosepticum
  • CAS No.: 9030-66-4
  • EC No.: 2.7.1.30
  • Source: Flavobacterium meningosepticum
  • Specific Activity:
Glycerol kinase from <i>Flavobacterium meningosepticum</i>
Inquiry

Copyright © Protheragen. All rights reserves.