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- Metabolism-Targeted Compounds
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- Oxidation-reduction-Targeted Compounds
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- Tyrosine Kinase/Adaptors-Targeted Compounds
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Tyrosine Kinase/Adaptors-Targeted Compounds
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LDN-214117 (OB0225LY-0184)
- CAS No.: 1627503-67-6
- Pathways: Tyrosine kinase/adaptors; Stem cells; Angiogenesis
- Targets: TGF-beta/Smad; ALK family
- Receptors: ALK2; TGF-β receptor
SM 16 (OB0225LY-0193)
- CAS No.: 614749-78-9
- Pathways: Tyrosine kinase/adaptors; Angiogenesis; Stem cells; TGF-β/Smad signaling
- Targets: ALK family
- Receptors: ALK4; ALK5
A 77-01 (OB0225LY-0194)
- CAS No.: 607737-87-1
- Pathways: TGF-beta/Smad signaling; Angiogenesis; Stem cells
- Targets: TGF-β receptor family
- Receptors: ALK5
Capivasertib (OB0225LY-0278)
- CAS No.: 1143532-39-1
- Pathways: Tyrosine kinase/adaptors; Cytoskeletal signaling; Autophagy; PI3K/Akt/mTOR signaling
- Targets: PI3K/Akt/mTOR pathway
- Receptors: Akt1; Akt2; Akt3; Autophagy; mTOR (p70S6K); PKA
AZ304 (OB0225LY-0314)
- CAS No.: 942507-42-8
- Pathways: Tyrosine kinase/adaptors; MAPK; Autophagy
- Targets: RTKs; Serine/Threonine kinases
- Receptors: B-Raf (V600E); B-Raf (WT); CSF1R; p38 MAPK; Raf
Piceatannol (OB0225LY-0316)
- CAS No.: 10083-24-6
- Pathways: Tyrosine kinase/adaptors; Apoptosis; Angiogenesis; Chromatin/Epigenetic; Metabolism; Autophagy; Cell cycle/Checkpoint; Cytoskeletal signaling
- Targets: Kinases
- Receptors: PKA; Autophagy; cAK; MLCK; PKC; Syk
Regorafenib (OB0225LY-0423)
- CAS No.: 755037-03-7
- Pathways: Tyrosine kinase/adaptors; MAPK; Autophagy; Angiogenesis; Apoptosis
- Targets: Kinases
- Receptors: c-Kit; PDGFR; Raf-1; c-RET; VEGFR1; VEGFR2
Biochanin A (OB0225LY-0427)
- CAS No.: 491-80-5
- Pathways: Tyrosine kinase/adaptors; Neuronal signaling; Autophagy; Angiogenesis; Metabolism; JAK/STAT signaling
- Targets: Enzymes
- Receptors: EGFR; FAAH
