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Alantolactone
Cat. No.:
OB0225WX-2750
Appearance:
Solid
Purity:
≥99%
Identity:
Confirmed by NMR, and HPLC.
Size:
Add to basket
Product Overview
Description:
Alantolactone is a natural eudesmane-type sesquiterpene lactone that triggers activin/SMAD3 signaling and interferes with the interaction between Cripto-1 and activin receptor type II A.
Synonym:
Helenin; Helenine; Eupatal; 546-43-0; Alant camphor; Inula camphor; Elecampane camphor; AI3-31147; (3aR,5S,8aR,9aR)-5,8a-dimethyl-3-methylidene-3a,5,6,7,8,8a,9,9a-octahydronaphtho[2,3-b]furan-2(3H)-one; Alantic anhydride; (3aR,5S,8aR,9aR)-5,8a-Dimethyl-3-methylene-3,3a,6,7,8,8a,9,9a-octahydronaphtho[2,3-b]furan-2(5H)-one; Naphtho[2,3-b]furan-2(3H)-one,3a,5,6,7,8,8a,9,9a-octahydro-5,8a-dimethyl-3-methylene-,(3aR,5S,8aR,9aR)-; 4alphaH-Eudesma-5,11(13)-dien-12-oic acid, 8beta-hydroxy-, gamma-lactone; (3aR,5S,8aR,9aR)-5,8a-dimethyl-3-methylidene-5,6,7,8,9,9a-hexahydro-3aH-benzo[f][1]benzofuran-2-one; Naphtho(2,3-b)furan-2(3H)-one, 3a,5,6,7,8,8a,9,9a-octahydro-5,8a-dimethyl-3-methylene-, (3aR-(3a alpha,5beta,8a beta,9a alpha))-; Helenine?; (+)-Alantolactone; (3aR,5S,8aR,9aR)-3a,5,6,7,8,8a,9,9a-Octahydro-5,8a-dimethyl-3-methylenenaphtho[2,3-b]furan-2(3H)-one; (3aR,5S,8aR,9aR)-5,8a-dimethyl-3-methylidene-3a,5,6,7,8,8a,9,9a-octahydronaphtho(2,3-b)furan-2(3H)-one; Naphtho[2,3-b]furan-2(3H)-one, 3a,5,6,7,8,8a,9,9a-octahydro-5,8a-dimethyl-3-methylene-, (3aR,5S,8aR,9aR)-
CAS No.:
546-43-0
Compound CID:
72724
Formula:
C15H20O2
Formula Weight:
232.32
Specification
Stability:
3 years in powder form.
Storage:
Storage at -20°C.
Applications:
Alantolactone is applied in phytochemical and oncology research as a natural sesquiterpene lactone to investigate the induction of apoptosis via the generation of reactive oxygen species and the inhibition of STAT3 signaling.
Library Information
Target:
Smad modulator; Receptor
Receptor:
Smad3; Activin receptor IIA
Pathways:
TGF-beta/Smad
Plate Number:
L6700-10
Empty Location:
a1-h1; a12-h12
Container:
96-well plate
Formulation:
10mM DMSO
DMSO Max Solubility:
46 mg/mL; 198 mM
Ethanol Max Solubility:
46 mg/mL
ALogP:
3.311
HBA_Count:
2
HBD_Count:
0
Rotatable Bond:
0





