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Kartogenin
Cat. No.:
OB0225WX-2695
Appearance:
Solid
Purity:
≥99%
Identity:
Confirmed by NMR, and HPLC.
Size:
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Product Overview
Description:
Kartogenin is a small-molecule activator of the Smad4/Smad5 signaling pathway that directs the selective differentiation of mesenchymal stem cells into chondrocytes.
Synonym:
KGN; 4727-31-5; 2-([1,1'-Biphenyl]-4-ylcarbamoyl)benzoic acid; 2-[(4-phenylphenyl)carbamoyl]benzoic acid; N-Biphenyl-4-yl-phthalamic acid; Phthalanilic acid, 4'-phenyl-; 2-[([1,1'-biphenyl]-4-ylamino)carbonyl]benzoic acid; Q93BBN11CP; 2-(4-Biphenylylcarbamoyl)benzoic acid; 2-((Biphenyl-4-yl)carbamoyl)benzoic acid; 2-((4-Phenylphenyl)carbamoyl)benzoic acid; 2-((4-Biphenylylamino)carbonyl)benzoic acid; 2-(N-(4-Phenylphenyl)carbamoyl)benzoic acid; J3.342.662C; MFCD00560510; 2-((1,1'-Biphenyl)-4-ylcarbamoyl)benzoic acid; 2-(((1,1'-Biphenyl)-4-ylamino)carbonyl)benzoic acid; Benzoic acid, 2-(((1,1'-biphenyl)-4-ylamino)carbonyl)-; 2-(biphenyl-4-ylcarbamoyl)benzoic acid; KGN; 2-[((1,1'-Biphenyl)-4-ylamino)carbonyl]benzoic acid
CAS No.:
4727-31-5
Compound CID:
2826191
Formula:
C20H15NO3
Formula Weight:
317.34
Specification
Stability:
3 years in powder form.
Storage:
Storage at -20°C.
Applications:
Kartogenin is employed in regenerative medicine as a potent small molecule to study the induction of mesenchymal stem cell differentiation into chondrocytes and the potential for articular cartilage repair.
Library Information
Target:
Smad pathway activator
Receptor:
Smad4; Smad5
Pathways:
TGF-beta/Smad
Plate Number:
L6700-09
Empty Location:
a1-h1; a12-h12
Container:
96-well plate
Formulation:
10mM DMSO
DMSO Max Solubility:
63 mg/mL; 198.53 mM
Ethanol Max Solubility:
18 mg/mL
ALogP:
3.762
HBA_Count:
2
HBD_Count:
1
Rotatable Bond:
4





