Overview

Insulin molecular metabolism is a complex and critical process that involves multiple aspects of insulin synthesis, secretion, transport, action, and degradation. Insulin molecular metabolism directly affects the cellular uptake of glucose, ultimately affecting energy metabolism throughout the body. Knowledge of insulin metabolism helps clients better understand the pathogenesis of diseases such as diabetes and obesity and enhances the treatment of these diseases. Protheragen provides reliable insulin molecular metabolism analysis. Our professional Obesity Pathobiology Research team provides high-quality Sugar-related Molecular Metabolism Analysis.

Insulin Metabolism Analysis in Obesity Pathology

Protheragen provides in-depth insulin metabolism analysis to help you better understand how insulin is metabolized in organisms and its role in disease progression.

• Insulin metabolic pathway analysis: Our researchers use advanced biotechnology to analyze the metabolic pathways of insulin in the body, including insulin synthesis, secretion, action, and its metabolites.
• Gene and protein expression analysis: Our researchers use gene sequencing and proteomics technologies to identify gene and protein expression changes associated with insulin metabolism.
• Personalized metabolic atlas construction: Our dedicated research team provides personalized metabolic network mapping to reveal patterns specific to insulin metabolism.

Professional Assay

• Immunoassays: Our company provides reliable immunoassay services such as enzyme-linked immunosorbent assay (ELISA), AlphaLISA, chemiluminescent immunoassay, radioimmunoassay (RIA), and so on.
• Chromatography: Our company provides high-performance micellar electrokinetic capillary chromatography (MECC) and liquid chromatography-tandem mass spectrometry (LC-MS/MS) analysis.
• Electrochemical biosensor: Our company offers high-sensitivity electrochemical biosensor analysis services. When insulin binds to the recognition element on the surface of the sensor, it causes a change in current or voltage, which enables quantitative analysis of insulin.

Workflow

Applications

• Insulin molecular metabolism analysis plays a crucial role in the regulation of glucose metabolism and lipid metabolism in the body.
• Analysis of abnormal insulin molecular metabolism plays a key role in disease discovery, diagnosis, and therapeutic research.
• Insulin molecular metabolism analysis provides critical data support in insulin analog drug delivery studies.

Advantages of Us

• Our MECC analysis service combines the advantages of both electrophoresis and chromatography for efficient separations in tiny capillaries.
• We offer LC-MS/MS with high resolution and sensitivity for accurate determination of insulin and its metabolites, especially for trace analysis in complex biological samples.
• Customized experimental procedures and diverse analytical techniques ensure that we meet all testing and research needs, providing reliable support for investigating the role of insulin molecular metabolism in obesity.

A Comprehensive Look at Our Obesity Research Lines

Publication Data

Frequently Asked Questions

1. What is the metabolic pathway of insulin analogs?

   The metabolic pathway of insulin mainly consists of its transport and degradation processes in organs such as the liver and kidneys, which ensure proper distribution and effective clearance of insulin in the body to maintain blood glucose stability. The fluid, liver, kidney, and small intestine are important sites for the degradation of insulin analogs as they are rich in various proteases and peptidases.

2. How does the insulin signaling pathway affect cell metabolism?

   Insulin promotes glucose uptake and utilization through glucose transporter type 4 (GLUT4) transport. Insulin further activates AKT, which expresses GLUT4 in Glut-4 vesicles, allowing it to be rapidly translocated from its internal storage site to the cell membrane, bringing glucose from the bloodstream into the interior of the cell for utilization. Insulin also promotes glycogen synthesis and storage, primarily through activation of glycogen synthase. In addition, insulin also promotes fatty acid synthesis and storage, and inhibits lipolysis and fat release, primarily by regulating a variety of enzymes and hormones related to lipid metabolism.

Protheragen provides comprehensive insulin molecular metabolism services to meet our clients' research needs. Our professional and conscientious work ethic is recognized by our clients. No matter what sugar molecule in obesity you want to analyze, please feel free to contact us.

All of our services and products are intended for preclinical research use only and cannot be used to diagnose, treat or manage patients.

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