Tofacitinib (CP-690550)

Cat. No.: OB0225WX-2518

Appearance: Solid

Purity: ≥99%

Identity: Confirmed by NMR, and HPLC.

Size:

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Product Overview

Description: Tofacitinib (CP-690550) is a pioneering inhibitor of JAK3 (IC50: 1 nM) that exhibits 20- to 100-fold higher potency compared to its activity against JAK1 and JAK2.

Synonym: Tasocitinib; 477600-75-2; 3-((3R,4R)-4-methyl-3-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)piperidin-1-yl)-3-oxopropanenitrile; CP-690550; CP 690550; 1259404-17-5; rac-Tofacitinib; CP-690,550; Cp-690 free base; tofacitinibum; Tofacitinib (CP-690550,Tasocitinib); 3-((3R,4R)-rel-4-Methyl-3-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)piperidin-1-yl)-3-oxopropanenitrile; 3-{(3R,4R)-4-methyl-3-[methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino]piperidin-1-yl}-3-oxopropanenitrile; 3-((3R,4R)-4-Methyl-3-(methyl(7H-pyrrolo(2,3-d)pyrimidin-4-yl)amino)piperidin-1-yl)-3-oxopropanenitrile; 3-[(3R,4R)-4-methyl-3-[methyl({7H-pyrrolo[2,3-d]pyrimidin-4-yl})amino]piperidin-1-yl]-3-oxopropanenitrile; 3-Piperidinamine, 1-(cyanoacetyl)-4-methyl-N-methyl-N-1H-pyrrolo(2,3-d)pyrimidin-4-yl-, (3R,4R)-; MFCD11035919; 3-[(3R*,4R*)-4-Methyl-3-[methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino]piperidin-1-yl]-3-oxopropanenitrile

CAS No.: 477600-75-2

Compound CID: 9926791

Formula: C₁₆H₂₀N₆

Formula Weight: 312.37

Specification

Stability: 3 years in powder form.

Storage: Storage at -20°C.

Applications: Tofacitinib (CP-690550) is applied in immunology research as a potent JAK inhibitor to investigate the suppression of cytokine-mediated signaling and its efficacy in models of autoimmune inflammation.