Products
- Anti-Obesity Compound Library
- GPCR/G Protein-Targeted Compounds
- Immunology/Inflammation-Targeted Compounds
- JAK/STAT-Targeted Compounds
- MAPK-Targeted Compounds
- Membrane Transporter/Ion Channel-Targeted Compounds
- Metabolism-Targeted Compounds
- NF-κB-Targeted Compounds
- Microbiology/Virology-Targeted Compounds
- Neuronal Signaling-Targeted Compounds
- PI3K/Akt/mTOR-Targeted Compounds
- Oxidation-reduction-Targeted Compounds
- Proteases/Proteasome-Targeted Compounds
- Stem Cells/Wnt-Targeted Compounds
- Tyrosine Kinase/Adaptors-Targeted Compounds
- Ubiquitin-Targeted Compounds
Online Inquiry
AS1517499
Cat. No.:
0225LY-0965
Appearance:
Solid
Purity:
≥98%
Identity:
Confirmed by NMR, HPLC, and LC-MS.
Size:
Add to basket
Product Overview
Description:
AS1517499 is a specialized STAT6 inhibitor with a reported IC50 of 21 nM.
Synonym:
919486-40-1; AS-1517499; 4-(Benzylamino)-2-((3-chloro-4-hydroxyphenethyl)amino)pyrimidine-5-carboxamide; 4-(benzylamino)-2-[2-(3-chloro-4-hydroxyphenyl)ethylamino]pyrimidine-5-carboxamide; 5-Pyrimidinecarboxamide, 2-((2-(3-chloro-4-hydroxyphenyl)ethyl)amino)-4-((phenylmethyl)amino)-; 4-(benzylamino)-2-{[2-(3-chloro-4-hydroxyphenyl)ethyl]amino}pyrimidine-5-carboxamide; 4-benzylamino-2-{[2-(3-chloro-4-hydroxyphenyl)ethyl]amino}pyrimidine-5-carboxamide
CAS No.:
919486-40-1
Compound CID:
10340781
Formula:
C20H20ClN5O2
Formula Weight:
397.86
Specification
Targets&IC50:
STAT6: 21 nM
Stability:
3 years in powder form.
Storage:
Storage at -20°C.
Applications:
AS1517499 can be used in immunology research to study the selective inhibition of the STAT6 signaling pathway.
Library Information
Target:
STAT
Receptor:
STAT6
Pathways:
JAK/STAT signaling; Stem cell regulation
Plate Number:
AOCL-13
Plate Location:
d6
Empty Location:
a1-h1; a12-h12
Container:
96-well plate
Formulation:
10mM DMSO
DMSO Max Solubility:
262.5 mg/mL; 659.78 mM
ALogP:
3.641
HBA_Count:
3
HBD_Count:
4
Rotatable Bond:
8
