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Casticin
Cat. No.:
0225LY-0976
Appearance:
Solid
Purity:
≥99%
Identity:
Confirmed by NMR, and HPLC.
Size:
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Product Overview
Description:
Casticin reduces vascular inflammation by targeting the ROS-NF-κB pathway and is considered a potential lead compound for prostate cancer therapy.
Synonym:
Quercetagetin 3,6,7,4'-Tetramethyl Ether; Vitexicarpin; 479-91-4; 5-hydroxy-2-(3-hydroxy-4-methoxyphenyl)-3,6,7-trimethoxychromen-4-one; Quercetagetin 3,6,7,4'-tetramethyl ether; 3',5-Dihydroxy-3,4',6,7-tetramethoxyflavone; 3,6,7,4'-Tetra-O-methyl-5,3'-dihydroxyflavone; 5-Hydroxy-2-(3-hydroxy-4-methoxyphenyl)-3,6,7-trimethoxy-4H-1-benzopyran-4-one; 5-hydroxy-2-(3-hydroxy-4-methoxyphenyl)-3,6,7-trimethoxy-4H-chromen-4-one; 4H-1-Benzopyran-4-one, 5-hydroxy-2-(3-hydroxy-4-methoxyphenyl)-3,6,7-trimethoxy-; 5-hydroxy-2-(3-hydroxy-4-methoxy-phenyl)-3,6,7-trimethoxy-chromen-4-one
CAS No.:
479-91-4
Compound CID:
5315263
Formula:
C19H18O8
Formula Weight:
374.34
Specification
Relative Density:
1.44 g/cm3
Stability:
3 years in powder form.
Storage:
Storage at -20°C.
Applications:
Casticin can be used in cancer biology to investigate its role in inducing mitotic arrest and apoptosis in malignant cells.
Library Information
Target:
STAT
Receptor:
STAT3
Pathways:
JAK/STAT signaling; Stem cell regulation
Plate Number:
AOCL-13
Plate Location:
e7
Empty Location:
a1-h1; a12-h12
Container:
96-well plate
Formulation:
10mM DMSO
DMSO Max Solubility:
137.5 mg/mL; 367.31 mM
Ethanol Max Solubility:
1 mg/mL; 2.67 mM
ALogP:
2.291
HBA_Count:
6
HBD_Count:
2
Rotatable Bond:
5
