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Mogrol
Cat. No.:
0225LY-0969
Appearance:
Solid
Purity:
≥99%
Identity:
Confirmed by NMR, HPLC, and LC-MS.
Size:
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Product Overview
Description:
Mogrol is a metabolite of mogrosides that activates AMPK signaling while simultaneously inhibiting CREB activation and the STAT3 and ERK1/2 pathways.
Synonym:
88930-15-8; (3S,8S,9R,10R,11R,13R,14S,17R)-17-[(2R,5R)-5,6-dihydroxy-6-methylheptan-2-yl]-4,4,9,13,14-pentamethyl-2,3,7,8,10,11,12,15,16,17-decahydro-1H-cyclopenta[a]phenanthrene-3,11-diol; (10alpha,24R)-9beta-Methyl-19-norlanosta-5-ene-3beta,11alpha,24,25-tetrol; (23R)-cucurbit-5-ene-3beta,11alpha,23,25-tetraol; (24R)-cucurbit-5-ene-3beta,11alpha,24,25-tetraol; (1S,4R,9beta,11alpha,24R)-9,10,14-trimethyl-4,9-cyclo-9,10-secocholest-5-ene-1,11,24,25-tetrol; (1R,3aS,3bS,7S,9aR,9bR,10R,11aR)-1-[(2R,5R)-5,6-dihydroxy-6-methylheptan-2-yl]-3a,6,6,9b,11a-pentamethyl-1H,2H,3H,3bH,4H,7H,8H,9H,9aH,10H,11H-cyclopenta[a]phenanthrene-7,10-diol; (3S,8S,9R,10R,11R,13R,14S,17R)-17-((2R,5R)-5,6-dihydroxy-6-methylheptan-2-yl)-4,4,9,13,14-pentamethyl-2,3,7,8,10,11,12,15,16,17-decahydro-1H-cyclopenta(a)phenanthrene-3,11-diol
CAS No.:
88930-15-8
Compound CID:
14525327
Formula:
C30H52O4
Formula Weight:
476.73
Specification
Relative Density:
1.10 g/cm3
Stability:
3 years in powder form.
Storage:
Storage at -20°C.
Applications:
Mogrol can be used in metabolic studies to examine its role as an AMPK activator in inhibiting lipid accumulation.
Library Information
Target:
ERK; STAT; AMPK
Receptor:
ERK1; ERK2; STAT3
Pathways:
JAK/STAT signaling; MAPK; PI3K/Akt/mTOR signaling; Chromatin/Epigenetic; Stem cell regulation
Plate Number:
AOCL-13
Plate Location:
d10
Empty Location:
a1-h1; a12-h12
Container:
96-well plate
Formulation:
10mM DMSO
DMSO Max Solubility:
110 mg/mL; 230.74 mM





