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Nifuroxazide
Cat. No.:
OB0225WX-2587
Appearance:
Solid
Purity:
≥99%
Identity:
Confirmed by NMR, and HPLC.
Size:
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Product Overview
Description:
Nifuroxazide is an orally bioavailable nitrofuran derivative that suppresses STAT1, STAT3, and STAT5 transcription activity, featuring an IC50 of 3 micromolar against IL-6-induced STAT3 activation.
Synonym:
965-52-6; Nifuroxazid; Dicoferin; Diarlidan; Nifuroxazida; Nifuroxazidum; Ercefurol; p-Hydroxybenzoic acid (5-nitrofurfurylidene)hydrazide; 4-Hydroxy-N'-((5-nitrofuran-2-yl)methylene)benzohydrazide; 4-Hydroxy-N'-(5-nitrofurfuryliden)benzhydrazid; p-Hydroxybenzoic acid 5-nitrofurfurylidene hydrazide; (Nitro-5' furfurylidene-2') hydroxy-4 benzhydrazide; 4-hydroxy-N-[(E)-(5-nitro-2-furyl)methyleneamino]benzamide; Benzoic acid, 4-hydroxy-, 2-[(5-nitro-2-furanyl)methylene]hydrazide; 4-hydroxy-N'-[(1E)-(5-nitrofuran-2-yl)methylidene]benzohydrazide; MFCD00079482
CAS No.:
965-52-6
Compound CID:
5337997
Formula:
C12H9N3O5
Formula Weight:
275.22
Specification
Stability:
3 years in powder form.
Storage:
Storage at -20°C.
Applications:
Nifuroxazide is employed in gastroenterology research as a nitrofuran antibiotic to investigate its localized antimicrobial effects in the intestinal tract and its impact on specific signaling pathways in cancer cells.
Library Information
Target:
STAT
Receptor:
STAT1; STAT3; STAT5
Pathways:
JAK/STAT
Plate Number:
L6700-06
Empty Location:
a1-h1; a12-h12
Container:
96-well plate
Formulation:
10mM DMSO
DMSO Max Solubility:
55 mg/mL; 199.84 mM
ALogP:
1.855
HBA_Count:
3
HBD_Count:
2
Rotatable Bond:
4
