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Timapiprant
Cat. No.:
0225LY-1143
Appearance:
Solid
Purity:
≥99%
Identity:
Confirmed by NMR.
Size:
Add to basket
Product Overview
Description:
Timapiprant functions as a selective and powerful antagonist of the D prostanoid receptor 2 (DP2), with an IC50 of 13 nM.
Synonym:
OC000459; 851723-84-7; Timapiprant; 2-(5-fluoro-2-methyl-3-(quinolin-2-ylmethyl)-1H-indol-1-yl)acetic acid; OC-000459; OC-459; ODC-9101; 2-[5-fluoro-2-methyl-3-(quinolin-2-ylmethyl)indol-1-yl]acetic Acid; OC459; 1H-Indole-1-acetic acid, 5-fluoro-2-methyl-3-(2-quinolinylmethyl)-; 04XB9TB8OL; (5-Fluoro-2-methyl-3-quinolin-2-ylmethylindo-1-yl)-acetic acid; [5-Fluoro-2-methyl-3-(2-quinolinylmethyl)-1H-indol-1-yl]acetic acid; Timapiprantum; 2-(5-fluoro-2-methyl-3-((quinolin-2-yl)methyl)-1H-indol-1-yl)acetic acid; 2-(5-fluoro-2-methyl-3-(quinolin-2-ylmethyl)indol-1-yl)acetic acid; 2-{5-fluoro-2-methyl-3-[(quinolin-2-yl)methyl]-1H-indol-1-yl}acetic acid
CAS No.:
851723-84-7
Compound CID:
11462174
Formula:
C21H17FN2O2
Formula Weight:
348.37
Specification
Targets&IC50:
DP2: 13 nM
Relative Density:
1.297 g/cm3
Stability:
3 years in powder form.
Storage:
Storage at -20°C.
Applications:
Timapiprant can be used in allergy research to investigate the potent antagonism of the CRTH2 receptor.
Library Information
Target:
GPR; Prostaglandin receptor
Receptor:
DP2; Prostaglandin receptor
Pathways:
Endocrinology/Hormones; GPCR/G protein signaling; Immunology/Inflammation
Plate Number:
AOCL-15
Plate Location:
f9
Empty Location:
a1-h1; a12-h12
Container:
96-well plate
Formulation:
10mM DMSO
DMSO Max Solubility:
3.49 mg/mL; 10.02 mM
Water Max Solubility:
<1 mg/mL (insoluble or slightly soluble)
Ethanol Max Solubility:
<1 mg/mL (insoluble or slightly soluble)
