Spironolactone

Cat. No.: OB0225WX-2579

Appearance: Solid

Purity: ≥99%

Identity: Confirmed by NMR, and HPLC.

Size:

INQUIRY Datasheet MSDS

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Product Overview

Description: Spironolactone is a steroidal small molecule that functions as a potent antagonist of the androgen receptor, exhibiting an IC50 of 77 nM.

Synonym: 52-01-7; Aldactone; Spirolactone; Verospirone; Euteberol; Verospiron; Spirolang; Acelat; Spironocompren; Melarcon; Spiresis; Spiridon; Spiroctan; Uractone; Urusonin; Alderon; Spirone; Xenalon; Dira; Spiro-Tablinen; Aldactone A; Spironolactone A; spironolattone; Spironolactonum; Aldopur; Aquareduct; Espironolactona; Almatol; Deverol; Aldace; Altex; Berlactone; Diatense; SC 9420; Spironolactone ceva; SC-9420; MFCD00082250; Spiro(17H-cyclopenta(a)phenauthrene-17,2'-(3'H)-furan); 7-alpha-Acetylthio-3-oxo-17-alpha-pregn-4-ene-21,17-beta-carbolactone; 17-Hydroxy-7-alpha-mercapto-3-oxo-17-alpha-pregn-4-ene-21-carboxylic acid-gamma-lactone-7-acetate; S-[(7R,8R,9S,10R,13S,14S,17R)-10,13-dimethyl-3,5'-dioxospiro[2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthrene-17,2'-oxolane]-7-yl] ethanethioate; Veroshpiron; 17-Hydroxy-7alpha-mercapto-3-oxo-17alpha-pregn-4-ene-21-carboxylic acid, gamma-lactone acetate; 3'-(3-Oxo-7-alpha-acetylthio-17-beta-hydroxyandrost-4-en-17-beta-yl)propionic acid lactone; S-[(7R,8R,9S,10R,13S,14S,17R)-10,13-dimethyl-3,5'-dioxo-1,2,3,4',5',6,7,8,9,10,11,12,13,14,15,16-hexadecahydro-3'H-spiro[cyclopenta[a]phenanthrene-17,2'-furan]-7-yl] ethanethioate

CAS No.: 52-01-7

Compound CID: 5833

Formula: C₂₄H₃₂O₄S

Formula Weight: 416.57

Specification

Stability: 3 years in powder form.

Storage: Storage at -20°C.

Applications: Spironolactone is employed in cardiovascular and endocrine research as a competitive mineralocorticoid receptor antagonist to investigate the regulation of fluid balance and the prevention of cardiac fibrosis.