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Fluorometholone acetate

Cat. No.: OB0225WX-2590
Appearance: Solid
Purity: ≥99%
Identity: Confirmed by NMR, and HPLC.
Size:
Fluorometholone acetate
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Product Overview

Description: Fluorometholone acetate is a synthetic corticosteroid derivative used at the molecular level to modulate steroid-responsive inflammatory signaling.
Synonym: NSC 47438; Oxylone acetate; 3801-06-7; Eflone; Flarex; Fluorometholone 17-acetate; Oxylone acetate; 9-Fluoro-11beta,17-dihydroxy-6alpha-methylpregna-1,4-diene-3,20-dione 17-acetate; 6alpha-Methyl-9alpha-fluoro-17-acetoxy-21-deoxyprednisolone; [(6S,8S,9R,10S,11S,13S,14S,17R)-17-acetyl-9-fluoro-11-hydroxy-6,10,13-trimethyl-3-oxo-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl] acetate; 9-fluoro-11beta-hydroxy-6alpha-methyl-3,20-dioxopregna-1,4-dien-17-yl acetate; (6alpha,11beta)-9-fluoro-11-hydroxy-6-methyl-3,20-dioxopregna-1,4-dien-17-yl acetate; Pregna-1,20-dione, 17-(acetyloxy)-9-fluoro-11-hydroxy-6-methyl-, (6.alpha.,11.beta.)-; Pregna-1,20-dione, 9-fluoro-11.beta.,17-dihydroxy-6.alpha.-methyl-, 17-acetate
CAS No.: 3801-06-7
Compound CID: 240767
Formula: C24H31FO5
Formula Weight: 418.5

Specification

Stability: 3 years in powder form.
Storage: Storage at -20°C.
Applications: Fluorometholone acetate is applied in ophthalmological research as a glucocorticoid to examine its efficacy in reducing ocular inflammation with a significantly lower risk of increasing intraocular pressure.

Library Information

Target: Glucocorticoid receptor
Pathways: Endocrinology & Hormones
Plate Number: L6700-06
Empty Location: a1-h1; a12-h12
Container: 96-well plate
Formulation: 10mM DMSO
DMSO Max Solubility: 83 mg/mL; 198.33 mM
Ethanol Max Solubility: 83 mg/mL
ALogP: 2.691
HBA_Count: 4
HBD_Count: 1
Rotatable Bond: 3
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