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Desoximetasone
Cat. No.:
OB0225WX-2632
Appearance:
Solid
Purity:
≥99%
Identity:
Confirmed by NMR, and HPLC.
Size:
Add to basket
Product Overview
Description:
Desoximetasone is a synthetic agonist of the glucocorticoid receptor that modulates metabolic, immunosuppressive, and anti-inflammatory signaling.
Synonym:
Desoxymethasone; Desoximetasonum; 382-67-2; Topicort; Desoximetasona; Desoximetasonum; Topicort LP; 17-Deoxydexamethasone; Desoxymetasone; Flubason; Desossimetasone; Esperson; HOE-304; 17-Deoxymethansone; 17-Desoximethasone; HOE 304; Deoxymethasone; 9-Fluoro-11beta,21-dihydroxy-16alpha-methylpregna-1,4-diene-3,20-dione; (8S,9R,10S,11S,13S,14S,16R,17S)-9-fluoro-11-hydroxy-17-(2-hydroxyacetyl)-10,13,16-trimethyl-7,8,11,12,14,15,16,17-octahydro-6H-cyclopenta[a]phenanthren-3-one; 9alpha-fluoro-16alpha-methyl-Delta(1)-corticosterone; 17 Desoxymethasone; 17-Desoxymethasone; A-41304; (11beta,16alpha)-9-Fluoro-11,21-dihydroxy-16-methylpregna-1,4-diene-3,20-dione; (8S,9R,10S,11S,13S,14S,16R,17S)-9-fluoro-11-hydroxy-17-(2-hydroxyacetyl)-10,13,16-trimethyl-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-3-one; 9-Fluoro-11-beta,21-dihydroxy-16-alpha-methylpregna-1,4-diene-3,20-dione; Pregna-1,4-diene-3,20-dione, 9-fluoro-11,21-dihydroxy-16-methyl-, (11beta,16alpha)-; 9alpha-fluoro-11beta,21-dihydroxy-16alpha-methyl-1.4-pregnadiene-3,20-dione; (1R,2S,10S,11S,13R,14S,15S,17S)-1-fluoro-17-hydroxy-14-(2-hydroxyacetyl)-2,13,15-trimethyltetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadeca-3,6-dien-5-one; (1S,2R,3aS,3bS,9aS,9bR,10S,11aS)-9b-fluoro-10-hydroxy-1-(2-hydroxyacetyl)-2,9a,11a-trimethyl-1H,2H,3H,3aH,3bH,4H,5H,7H,9aH,9bH,10H,11H,11aH-cyclopenta[a]phenanthren-7-one
CAS No.:
382-67-2
Compound CID:
5311067
Formula:
C22H29FO4
Formula Weight:
376.46
Specification
Stability:
3 years in powder form.
Storage:
Storage at -20°C.
Applications:
Desoximetasone is used in dermatological pharmacology as a potent glucocorticoid to investigate the regulation of inflammatory mediators and the reduction of epidermal hyperproliferation in topical disease models.
Library Information
Target:
Glucocorticoid receptor
Pathways:
Endocrinology & Hormones
Plate Number:
L6700-07
Empty Location:
a1-h1; a12-h12
Container:
96-well plate
Formulation:
10mM DMSO
DMSO Max Solubility:
75 mg/mL; 199.22 mM
Ethanol Max Solubility:
75 mg/mL
ALogP:
2.376
HBA_Count:
2
HBD_Count:
2
Rotatable Bond:
2





