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Desoximetasone

Cat. No.: OB0225WX-2632
Appearance: Solid
Purity: ≥99%
Identity: Confirmed by NMR, and HPLC.
Size:
Desoximetasone
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Product Overview

Description: Desoximetasone is a synthetic agonist of the glucocorticoid receptor that modulates metabolic, immunosuppressive, and anti-inflammatory signaling.
Synonym: Desoxymethasone; Desoximetasonum; 382-67-2; Topicort; Desoximetasona; Desoximetasonum; Topicort LP; 17-Deoxydexamethasone; Desoxymetasone; Flubason; Desossimetasone; Esperson; HOE-304; 17-Deoxymethansone; 17-Desoximethasone; HOE 304; Deoxymethasone; 9-Fluoro-11beta,21-dihydroxy-16alpha-methylpregna-1,4-diene-3,20-dione; (8S,9R,10S,11S,13S,14S,16R,17S)-9-fluoro-11-hydroxy-17-(2-hydroxyacetyl)-10,13,16-trimethyl-7,8,11,12,14,15,16,17-octahydro-6H-cyclopenta[a]phenanthren-3-one; 9alpha-fluoro-16alpha-methyl-Delta(1)-corticosterone; 17 Desoxymethasone; 17-Desoxymethasone; A-41304; (11beta,16alpha)-9-Fluoro-11,21-dihydroxy-16-methylpregna-1,4-diene-3,20-dione; (8S,9R,10S,11S,13S,14S,16R,17S)-9-fluoro-11-hydroxy-17-(2-hydroxyacetyl)-10,13,16-trimethyl-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-3-one; 9-Fluoro-11-beta,21-dihydroxy-16-alpha-methylpregna-1,4-diene-3,20-dione; Pregna-1,4-diene-3,20-dione, 9-fluoro-11,21-dihydroxy-16-methyl-, (11beta,16alpha)-; 9alpha-fluoro-11beta,21-dihydroxy-16alpha-methyl-1.4-pregnadiene-3,20-dione; (1R,2S,10S,11S,13R,14S,15S,17S)-1-fluoro-17-hydroxy-14-(2-hydroxyacetyl)-2,13,15-trimethyltetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadeca-3,6-dien-5-one; (1S,2R,3aS,3bS,9aS,9bR,10S,11aS)-9b-fluoro-10-hydroxy-1-(2-hydroxyacetyl)-2,9a,11a-trimethyl-1H,2H,3H,3aH,3bH,4H,5H,7H,9aH,9bH,10H,11H,11aH-cyclopenta[a]phenanthren-7-one
CAS No.: 382-67-2
Compound CID: 5311067
Formula: C22H29FO4
Formula Weight: 376.46

Specification

Stability: 3 years in powder form.
Storage: Storage at -20°C.
Applications: Desoximetasone is used in dermatological pharmacology as a potent glucocorticoid to investigate the regulation of inflammatory mediators and the reduction of epidermal hyperproliferation in topical disease models.

Library Information

Target: Glucocorticoid receptor
Pathways: Endocrinology & Hormones
Plate Number: L6700-07
Empty Location: a1-h1; a12-h12
Container: 96-well plate
Formulation: 10mM DMSO
DMSO Max Solubility: 75 mg/mL; 199.22 mM
Ethanol Max Solubility: 75 mg/mL
ALogP: 2.376
HBA_Count: 2
HBD_Count: 2
Rotatable Bond: 2
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