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Deflazacort

Cat. No.: OB0225WX-2452
Appearance: Solid
Purity: ≥99%
Identity: Confirmed by NMR, and HPLC.
Size:
Deflazacort
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Product Overview

Description: Deflazacort is an oxazoline derivative of prednisolone that functions as a systemic glucocorticoid and immunosuppressive agent.
Synonym: MDL 458; 14484-47-0; Azacort; Calcort; Emflaza; Flantadin; Oxazacort; Lantadin; Deflan; Deflazacortum; Enzocort; Cortax; MDL 458; DL-458-IT; MDL-458; MFCD00866106; 2-((6aR,6bS,7S,8aS,8bS,11aR,12aS,12bS)-7-hydroxy-6a,8a,10-trimethyl-4-oxo-1,2,4,6a,6b,7,8,8a,11a,12,12a,12b-dodecahydro-8bH-naphtho[2',1':4,5]indeno[1,2-d]oxazol-8b-yl)-2-oxoethyl acetate; Dezacor; [2-[(1S,2S,4R,8S,9S,11S,12S,13R)-11-hydroxy-6,9,13-trimethyl-16-oxo-5-oxa-7-azapentacyclo[10.8.0.02,9.04,8.013,18]icosa-6,14,17-trien-8-yl]-2-oxoethyl] acetate; 2-[(4aR,4bS,5S,6aS,6bS,9aR,10aS,10bS)-5-hydroxy-4a,6a,8-trimethyl-2-oxo-2,4a,4b,5,6,6a,9a,10,10a,10b,11,12-dodecahydro-6bH-naphtho[2',1':4,5]indeno[1,2-d][1,3]oxazol-6b-yl]-2-oxoethyl acetate; Deflazacort [USAN:INN:BAN]; (11beta,16beta)-21-(Acetyloxy)-11-hydroxy-2'-methyl-5'H-pregna-1,4-dieno(17,16-d)oxazole-3,20-dione; (11beta,16beta)-21-(acetyloxy)-11-hydroxy-2'-methyl-5'H-pregna-1,4-dieno[17,16-d]oxazole-3,20-dione
CAS No.: 14484-47-0
Compound CID: 189821
Formula: C25H31NO6
Formula Weight: 441.52

Specification

Stability: 3 years in powder form.
Storage: Storage at -20°C.
Applications: Deflazacort is used in musculoskeletal research as an oxazoline derivative of prednisolone to investigate the maintenance of muscle strength and the reduction of inflammatory damage in dystrophy models.

Library Information

Target: Glucocorticoid receptor
Pathways: Endocrinology & Hormones
Plate Number: L6700-02
Empty Location: a1-h1; a12-h12
Container: 96-well plate
Formulation: 10mM DMSO
DMSO Max Solubility: 88 mg/mL; 199.31 mM
Ethanol Max Solubility: 12 mg/mL
ALogP: 1.67
HBA_Count: 6
HBD_Count: 1
Rotatable Bond: 4
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