Canrenone

Cat. No.: OB0225WX-2619

Appearance: Solid

Purity: ≥99%

Identity: Confirmed by NMR, and HPLC.

Size:

INQUIRY Datasheet MSDS

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Product Overview

Description: Canrenone is a steroidal cardiovascular agent and the primary active metabolite of spironolactone, functioning as a nonselective aldosterone receptor antagonist.

Synonym: Aldadiene; SC-9376; RP-11614; 6,7-Dehydro-7α-desthioacetylspironolactone; Phanurane; Luvion; Canrenona; Canrenonum; MFCD00071735; 17-Hydroxy-3-oxo-17alpha-pregna-4,6-diene-21-carboxylic acid gamma-lactone; (8R,9S,10R,13S,14S,17R)-10,13-dimethylspiro[2,8,9,11,12,14,15,16-octahydro-1H-cyclopenta[a]phenanthrene-17,5'-oxolane]-2',3-dione; 17alpha-(2-Carboxyethyl)-17beta-hydroxyandrosta-4,6-dien-3-one lactone; 5-17-11-00476 (Beilstein Handbook Reference); 20-Spiroxa-4,6-diene-3,21-dione; (1'S,2R,2'R,10'R,11'S,15'S)-2',15'-dimethylspiro[oxolane-2,14'-tetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadecane]-6',8'-diene-5,5'-dione; 17alpha-Pregna-4,6-diene-21-carboxylic acid, 17-hydroxy-3-oxo-, gamma-lactone; Pregna-4,6-diene-21-carboxylic acid, 17-hydroxy-3-oxo-, g-lactone,(17a)-; Pregna-4,6-diene-21-carboxylic acid, 17-hydroxy-3-oxo-, gamma-lactone (17alpha)-; Canrenon; (10R,13S,17R)-10,13-dimethylspiro[2,8,9,11,12,14,15,16-octahydro-1H-cyclopenta[a]phenanthrene-17,5'-oxolane]-2',3-dione; 17b-Hydroxy-3-oxopregna-4,6-diene-21-carboxylic acid; 17-Hydroxy-3-oxo-17a-pregna-4,6-diene-21-carboxylic acid g-lactone; 17-Hydroxy-3-oxo-17a-pregna-4,6-diene-21-carboxylic acid lactone; 17a-(2-Carboxyethyl)-17b-hydroxyandrosta-4,6-dien-3-one lactone; 3-(17b-Hydroxy-3-oxoandrosta-4,6-dien-17a-yl)propionic acid lactone; 3'-(3-Oxo-17b-hydroxyandrosta-4,6-dien-17a-yl)-propionic acid lactone; 3-(17b-Hydroxy-3-oxoandrosta-4,6-dien-17a-yl)propionic acid g-lactone; 3-(3-Oxo-17b-hydroxy-4,6-androstadien-17a-yl)propionic acid g-lactone; Pregna-4,6-diene-21-carboxylic acid, 17-hydroxy-3-oxo-, .gamma.-lactone (17.alpha.)-

CAS No.: 976-71-6

Compound CID: 13789

Formula: C₂₂H₂₈O₃

Formula Weight: 340.46

Specification

Stability: 3 years in powder form.

Storage: Storage at -20°C.

Applications: Canrenone is utilized in cardiovascular pharmacology as the primary active metabolite of spironolactone to study the antagonism of the mineralocorticoid receptor and the regulation of electrolyte balance.