Fasiglifam(TAK-875) Hemihydrate

Cat. No.: OB0225WX-2505

Appearance: Solid

Purity: ≥99%

Identity: Confirmed by NMR, and HPLC.

Size:

INQUIRY Datasheet MSDS

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Product Overview

Description: Fasiglifam (TAK-875) Hemihydrate is a high-affinity GPR40 agonist featuring an EC50 of 14 nM, making it approximately 400 times more potent than oleic acid in human GPR40-expressing cells.

Synonym: 1374598-80-7; Fasiglifam hemihydrate; TAK875; (3S)-6-((2',6'-Dimethyl-4'-(3-(methylsulfonyl)propoxy) biphenyl-3-yl)methoxy)-2,3-dihydro-l-benzofuran-3-yl)acetic acid hemihydrate; (3S)-6-((2',6'-Dimethyl-4'-(3-(methylsulfonyl)propoxy) biphenyl-3-yl)methoxy)-2,3-dihydro-l-benzofuran-3-yl)acetic acid hydrate; 2-[(3S)-6-[[3-[2,6-dimethyl-4-(3-methylsulfonylpropoxy)phenyl]phenyl]methoxy]-2,3-dihydro-1-benzofuran-3-yl]acetic acid;hydrate; 3-Benzofuranacetic acid, 6-((2',6'-dimethyl-4'-(3-(methylsulfonyl)propoxy)(1,1'-biphenyl)-3-yl)methoxy)-2,3-dihydro-, hydrate (2:1), (3S)-; ((3S)-6-((2',6'-Dimethyl-4'-(3-(methylsulfonyl)propyloxy)biphenyl-3-yl)methoxy)-2,3-dihydro-1-benzofuran-3-yl)acetic acid hemihydrate; [(3S)-6-({2',6'-Dimethyl-4'-[3-(methylsulfonyl)propyloxy]biphenyl-3-yl}methoxy)-2,3-dihydro-1-benzofuran-3-yl]acetic acid hemihydrate; 3-Benzofuranacetic acid, 6-[[2',6'-dimethyl-4'-[3-(methylsulfonyl)propoxy][1,1'-biphenyl]-3-yl]methoxy]-2,3-dihydro-, hydrate (2:1), (3S)-

CAS No.: 1374598-80-7

Compound CID: 57339446

Formula: C₂₉H₃₂O₇S·1/2H₂O

Formula Weight: 533.63

Specification

Stability: 3 years in powder form.

Storage: Storage at -20°C.

Applications: Fasiglifam (TAK-875) Hemihydrate is utilized in diabetes research as a selective GPR40 agonist to investigate the glucose-dependent stimulation of insulin secretion from pancreatic beta cells.