Galeterone

Cat. No.: OB0225WX-2520

Appearance: Solid

Purity: ≥99%

Identity: Confirmed by NMR, and HPLC.

Size:

INQUIRY Datasheet MSDS

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Product Overview

Description: Galeterone is a dual-function molecule that acts as both a selective CYP17 inhibitor (IC50: 300 nM) and an androgen receptor (AR) antagonist (IC50: 384 nM).

Synonym: TOK-001; 851983-85-2; VN/124-1; Galaterone; TOK 001; (3S,8R,9S,10R,13S,14S)-17-(benzimidazol-1-yl)-10,13-dimethyl-2,3,4,7,8,9,11,12,14,15-decahydro-1H-cyclopenta[a]phenanthren-3-ol; 3-hydroxy-17-(1H-benzimidazole-1-yl)androsta-5,16-diene; 17-(1H-Benzimidazol-1-yl)androsta-5,16-dien-3beta-ol; (3S,8R,9S,10R,13S,14S)-17-(1H-Benzo[d]imidazol-1-yl)-10,13-dimethyl-2,3,4,7,8,9,10,11,12,13,14,15-dodecahydro-1H-cyclopenta[a]phenanthren-3-ol; Androsta-5,16-dien-3-ol, 17-(1H-benzimidazol-1-yl)-, (3beta)-; (3beta)-17-(1h-benzimidazol-1-yl)androsta-5,16-dien-3-ol; (1S,2R,5S,10R,11S,15S)-14-(1H-1,3-benzodiazol-1-yl)-2,15-dimethyltetracyclo(8.7.0.02,?.011,1?)heptadeca-7,13-dien-5-ol; (1S,2R,5S,10R,11S,15S)-14-(1H-1,3-benzodiazol-1-yl)-2,15-dimethyltetracyclo[8.7.0.02,?.011,1?]heptadeca-7,13-dien-5-ol; (3S,8R,9S,10R,13S,14S)-17-(benzimidazol-1-yl)-10,13-dimethyl-2,3,4,7,8,9,11,12,14,15-decahydro-1H-cyclopenta(a)phenanthren-3-ol; MFCD16660907

CAS No.: 851983-85-2

Compound CID: 11188409

Formula: C₂₆H₃₂N₂

Formula Weight: 388.55

Specification

Stability: 3 years in powder form.

Storage: Storage at -20°C.

Applications: Galeterone is employed in endocrine oncology research as a multi-target agent to investigate the inhibition of CYP17, androgen receptor antagonism, and the induction of androgen receptor degradation.