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EPI-001
Cat. No.:
0225LY-0822
Appearance:
Solid
Purity:
≥99%
Identity:
Confirmed by NMR, HPLC, and LC-MS.
Size:
Add to basket
Product Overview
Description:
EPI-001 functions as a selective modulator of PPAR-gamma and an antagonist of the androgen receptor N-terminal domain (IC50: approximately 6 uM).
Synonym:
EPI001; EPI 001; 227947-06-0; Bisphenol A (3-chloro-2-hydroxypropyl) (2,3-dihydroxypropyl) ether; 3-[4-[1-[4-(3-Chloro-2-hydroxypropoxy)phenyl]-1-methylethyl]phenoxy]-1,2-propanediol; 3-[4-[2-[4-(3-chloro-2-hydroxypropoxy)phenyl]propan-2-yl]phenoxy]propane-1,2-diol; CHEMBL4758041; 3-(4-{2-[4-(3-chloro-2-hydroxypropoxy)phenyl]propan-2-yl}phenoxy)propane-1,2-diol; BADGE-HCl-H2O; 3-(4-(2-(4-(3-Chloro-2-hydroxypropoxy)phenyl)propan-2-yl)phenoxy)propane-1,2-diol; 1,2-Propanediol, 3-[4-[1-[4-(3-chloro-2-hydroxypropoxy)phenyl]-1-methylethyl]phenoxy]-
CAS No.:
227947-06-0
Compound CID:
4166922
Formula:
C21H27ClO5
Formula Weight:
394.89
Specification
Targets&IC50:
Androgen receptor: 6 μM
Relative Density:
1.228 g/cm3
Stability:
3 years in powder form.
Storage:
Storage at -20°C.
Applications:
EPI-001 can be used in prostate cancer research to study the targeted inhibition of the androgen receptor N-terminal domain.
Library Information
Target:
Androgen receptor; PPAR
Receptor:
Androgen receptor; PPAR
Pathways:
Endocrinology/Hormones; DNA damage/DNA repair; Apoptosis; Metabolism
Plate Number:
AOCL-11
Plate Location:
e11
Empty Location:
a1-h1; a12-h12
Container:
96-well plate
Formulation:
10mM DMSO
DMSO Max Solubility:
55 mg/mL; 139.28 mM
Water Max Solubility:
<1 mg/mL (insoluble or slightly soluble)
Ethanol Max Solubility:
70 mg/mL; 177.26 mM
