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Astragaloside IV
Cat. No.:
0225LY-1071
Appearance:
Solid
Purity:
≥99%
Identity:
Confirmed by NMR, HPLC, and LC-MS.
Size:
Add to basket
Product Overview
Description:
Astragaloside IV is a bioactive saponin from Astragalus membranaceus that provides systemic protection for the nervous and cardiovascular systems; it suppresses JNK and ERK1/2 activation, reduces viral replication of HAdV-3, and downregulates MMP-2 and MMP-9 in breast cancer cells.
Synonym:
AST-IV; AS-IV; 84687-43-4; Cyclosiversioside F; (2R,3R,4S,5S,6R)-2-[[(1S,3R,6S,8R,9S,11S,12S,14S,15R,16R)-14-hydroxy-15-[(2R,5S)-5-(2-hydroxypropan-2-yl)-2-methyloxolan-2-yl]-7,7,12,16-tetramethyl-6-[(2S,3R,4S,5R)-3,4,5-trihydroxyoxan-2-yl]oxy-9-pentacyclo[9.7.0.01,3.03,8.012,16]octadecanyl]oxy]-6-(hydroxymethyl)oxane-3,4,5-triol; Astrasieversianin XIV; 3-O-beta-D-xylopyranosyl-6-O-beta-D-glucopyranosylcycloastragenol; (2R,3R,4S,5S,6R)-2-[[(1S,3R,8R,9S,11S,12S,14S,15R,16R)-14-Hydroxy-15-[(2R,5S)-5-(2-hydroxypropan-2-yl)-2-methyloxolan-2-yl]-7,7,12,16-tetramethyl-6-[(2S,3R,4S,5R)-3,4,5-trihydroxyoxan-2-yl]oxy-9-pentacyclo[9.7.0.01,3.03,8.012,16]octadecanyl]oxy]-6-(hydroxymethyl)oxane-3,4,5-triol; beta-D-Glucopyranoside, (3beta,6alpha,16beta,20R,24S)-20,24-epoxy-16,25-dihydroxy-3-(beta-D-xylopyranosyloxy)-9,19-cyclolanostan-6-yl; AstragalosideIV
CAS No.:
84687-43-4
Compound CID:
13943297
Formula:
C41H68O14
Formula Weight:
784.97
Specification
Relative Density:
1.39 g/cm3
Stability:
3 years in powder form.
Storage:
Storage at -20°C.
Applications:
Astragaloside IV can be used in cardiovascular research or play an important role in studies on myocardial protection and anti-fibrotic mechanisms.
Library Information
Target:
JNK; MMP; ERK; Estrogen/progestogen receptor
Receptor:
ERK; ERS; JNK; MMP
Pathways:
Endocrinology/Hormones; Proteases/Proteasome; MAPK
Plate Number:
AOCL-14
Plate Location:
g6
Empty Location:
a1-h1; a12-h12
Container:
96-well plate
Formulation:
10mM DMSO
DMSO Max Solubility:
100 mg/mL; 127.39 mM
ALogP:
-0.348
HBA_Count:
5
HBD_Count:
8
Rotatable Bond:
7





