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Vitamin B12 test kit

Astragaloside IV

Cat. No.: 0225LY-1071
Appearance: Solid
Purity: ≥99%
Identity: Confirmed by NMR, HPLC, and LC-MS.
Size:
Astragaloside IV
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Product Overview

Description: Astragaloside IV is a bioactive saponin from Astragalus membranaceus that provides systemic protection for the nervous and cardiovascular systems; it suppresses JNK and ERK1/2 activation, reduces viral replication of HAdV-3, and downregulates MMP-2 and MMP-9 in breast cancer cells.
Synonym: AST-IV; AS-IV; 84687-43-4; Cyclosiversioside F; (2R,3R,4S,5S,6R)-2-[[(1S,3R,6S,8R,9S,11S,12S,14S,15R,16R)-14-hydroxy-15-[(2R,5S)-5-(2-hydroxypropan-2-yl)-2-methyloxolan-2-yl]-7,7,12,16-tetramethyl-6-[(2S,3R,4S,5R)-3,4,5-trihydroxyoxan-2-yl]oxy-9-pentacyclo[9.7.0.01,3.03,8.012,16]octadecanyl]oxy]-6-(hydroxymethyl)oxane-3,4,5-triol; Astrasieversianin XIV; 3-O-beta-D-xylopyranosyl-6-O-beta-D-glucopyranosylcycloastragenol; (2R,3R,4S,5S,6R)-2-[[(1S,3R,8R,9S,11S,12S,14S,15R,16R)-14-Hydroxy-15-[(2R,5S)-5-(2-hydroxypropan-2-yl)-2-methyloxolan-2-yl]-7,7,12,16-tetramethyl-6-[(2S,3R,4S,5R)-3,4,5-trihydroxyoxan-2-yl]oxy-9-pentacyclo[9.7.0.01,3.03,8.012,16]octadecanyl]oxy]-6-(hydroxymethyl)oxane-3,4,5-triol; beta-D-Glucopyranoside, (3beta,6alpha,16beta,20R,24S)-20,24-epoxy-16,25-dihydroxy-3-(beta-D-xylopyranosyloxy)-9,19-cyclolanostan-6-yl; AstragalosideIV
CAS No.: 84687-43-4
Compound CID: 13943297
Formula: C41H68O14
Formula Weight: 784.97

Specification

Relative Density: 1.39 g/cm3
Stability: 3 years in powder form.
Storage: Storage at -20°C.
Applications: Astragaloside IV can be used in cardiovascular research or play an important role in studies on myocardial protection and anti-fibrotic mechanisms.

Library Information

Target: JNK; MMP; ERK; Estrogen/progestogen receptor
Receptor: ERK; ERS; JNK; MMP
Pathways: Endocrinology/Hormones; Proteases/Proteasome; MAPK
Plate Number: AOCL-14
Plate Location: g6
Empty Location: a1-h1; a12-h12
Container: 96-well plate
Formulation: 10mM DMSO
DMSO Max Solubility: 100 mg/mL; 127.39 mM
ALogP: -0.348
HBA_Count: 5
HBD_Count: 8
Rotatable Bond: 7
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