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Flumethasone
Cat. No.:
OB0225WX-2582
Appearance:
Solid
Purity:
≥99%
Identity:
Confirmed by NMR, and HPLC.
Size:
Add to basket
Product Overview
Description:
Flumethasone is a glucocorticoid receptor agonist that exerts its biological effect by binding to the receptor and translocating to the nucleus to modulate gene activation and repression.
Synonym:
RS-2177, 2135-17-3; Flumetasone; Flucorticin; Flumethason; Anaprime; Methagon; Fluvet; Aniprime; Cortexilar; RS 2177; Flumetasona; Flumetasonum; Flumethasonum; 6alpha-Fluorodexamethasone; 6-alpha-Fluorodexamethasone; 6alpha,9-Difluoro-11beta,17,21-trihydroxy-16alpha-methylpregna-1,4-diene-3,20-dione; 6alpha,9alpha-Difluoro-16alpha-methylprednisolone; (6S,8S,9R,10S,11S,13S,14S,16R,17R)-6,9-difluoro-11,17-dihydroxy-17-(2-hydroxyacetyl)-10,13,16-trimethyl-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-3-one; Fluorodexamethasone; MFCD00056464; (6S,8S,9R,10S,11S,13S,14S,16R,17R)-6,9-difluoro-11,17-dihydroxy-17-(2-hydroxyacetyl)-10,13,16-trimethyl-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-3-one
CAS No.:
2135-17-3
Compound CID:
16490
Formula:
C22H28F2O5
Formula Weight:
410.45
Specification
Stability:
3 years in powder form.
Storage:
Storage at -20°C.
Applications:
Flumethasone is applied in pharmacological studies as a potent fluorinated corticosteroid to investigate the suppression of local inflammatory responses and the modulation of gene expression in skin and joint tissues.
Library Information
Target:
Glucocorticoid receptor
Pathways:
Endocrinology & Hormones
Plate Number:
L6700-06
Empty Location:
a1-h1; a12-h12
Container:
96-well plate
Formulation:
10mM DMSO
DMSO Max Solubility:
82 mg/mL; 199.78 mM
Ethanol Max Solubility:
6 mg/mL
ALogP:
1.546
HBA_Count:
2
HBD_Count:
2
Rotatable Bond:
2





