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Vitamin B12 test kit

Flumethasone

Cat. No.: OB0225WX-2582
Appearance: Solid
Purity: ≥99%
Identity: Confirmed by NMR, and HPLC.
Size:
Flumethasone
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Product Overview

Description: Flumethasone is a glucocorticoid receptor agonist that exerts its biological effect by binding to the receptor and translocating to the nucleus to modulate gene activation and repression.
Synonym: RS-2177, 2135-17-3; Flumetasone; Flucorticin; Flumethason; Anaprime; Methagon; Fluvet; Aniprime; Cortexilar; RS 2177; Flumetasona; Flumetasonum; Flumethasonum; 6alpha-Fluorodexamethasone; 6-alpha-Fluorodexamethasone; 6alpha,9-Difluoro-11beta,17,21-trihydroxy-16alpha-methylpregna-1,4-diene-3,20-dione; 6alpha,9alpha-Difluoro-16alpha-methylprednisolone; (6S,8S,9R,10S,11S,13S,14S,16R,17R)-6,9-difluoro-11,17-dihydroxy-17-(2-hydroxyacetyl)-10,13,16-trimethyl-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-3-one; Fluorodexamethasone; MFCD00056464; (6S,8S,9R,10S,11S,13S,14S,16R,17R)-6,9-difluoro-11,17-dihydroxy-17-(2-hydroxyacetyl)-10,13,16-trimethyl-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-3-one
CAS No.: 2135-17-3
Compound CID: 16490
Formula: C22H28F2O5
Formula Weight: 410.45

Specification

Stability: 3 years in powder form.
Storage: Storage at -20°C.
Applications: Flumethasone is applied in pharmacological studies as a potent fluorinated corticosteroid to investigate the suppression of local inflammatory responses and the modulation of gene expression in skin and joint tissues.

Library Information

Target: Glucocorticoid receptor
Pathways: Endocrinology & Hormones
Plate Number: L6700-06
Empty Location: a1-h1; a12-h12
Container: 96-well plate
Formulation: 10mM DMSO
DMSO Max Solubility: 82 mg/mL; 199.78 mM
Ethanol Max Solubility: 6 mg/mL
ALogP: 1.546
HBA_Count: 2
HBD_Count: 2
Rotatable Bond: 2
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