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Clobetasol propionate

Cat. No.: OB0225WX-2498
Appearance: Solid
Purity: ≥99%
Identity: Confirmed by NMR, and HPLC.
Size:
Clobetasol propionate
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Product Overview

Description: Clobetasol propionate is a highly potent Class I corticosteroid characterized by its significant anti-inflammatory molecular activity.
Synonym: CGP9555, CCl 4725; 25122-46-7; Clobetasol 17-propionate; Clobex; Dermovate; Temovate; Embeline; Clobesol; Cormax; Olux; Temovate E; Olux-E; Dermoxinale; Butavate; Dermoval; Yugofin; Impoyz; Psorex; Clobetasolpropionate; Olux E; Clobestasol propionate; [(8S,9R,10S,11S,13S,14S,16S,17R)-17-(2-chloroacetyl)-9-fluoro-11-hydroxy-10,13,16-trimethyl-3-oxo-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl] propanoate; Pregna-1,4-diene-3,20-dione, 21-chloro-9-fluoro-11-hydroxy-16-methyl-17-(1-oxopropoxy)-, (11beta,16beta)-; Clobetasol propionate gel; Clobetasol-17-propionate; 21-Chloro-9-fluoro-11beta,17-dihydroxy-16beta-methylpregna-1,4-diene-3,20-dione 17-propionate; MFCD00058499; 21-Chloro-9-fluoro-11-hydroxy-16-methyl-17-(1-oxopropoxy)pregna-1,4-diene-3,20-dione (11beta,16beta)-; 21-chloro-9-fluoro-11beta-hydroxy-16beta-methyl-3,20-dioxopregna-1,4-dien-17-yl propanoate; 21-Chloro-9-fluoro-11beta-hydroxy-16beta-methylpregna-1,4-diene-3,20-dione 17-propionate; Pregna-1,4-diene-3,20-dione, 21-chloro-9-fluoro-11-beta,17-dihydroxy-16-beta-methyl-, 17-propionate; Pregna-1,4-diene-3,20-dione, 21-chloro-9-fluoro-11-hydroxy-16-methyl-17-(1-oxopropoxy)-, (11.beta.,16.beta.)-; clobetasol-propionate; (11b,16b)-21-Chloro-9-fluoro-11-hydroxy-16-methyl-17-(1-oxopropoxy)pregna-1,4-diene-3,20-dione; (1R,2S,3aS,3bS,9aS,9bR,10S,11aS)-1-(2-chloroacetyl)-9b-fluoro-10-hydroxy-2,9a,11a-trimethyl-7-oxo-1H,2H,3H,3aH,3bH,4H,5H,7H,9aH,9bH,10H,11H,11aH-cyclopenta[a]phenanthren-1-yl propanoate; (8alpha,11beta,14beta,16alpha,17alpha)-21-chloro-9-fluoro-11-hydroxy-16-methyl-3,20-dioxopregna-1,4-dien-17-yl propanoate; 21-Chloro-9-fluoro-11beta,17-dihydroxy-16beta-methylpregna-1,4-diene-3,20-dione 17-propanoate; 21-Chloro-9alpha-fluoro-11beta,17alpha-dihydroxy-16beta-methyl-1,4-pregnadiene-3,20-dione 17-Propionate
CAS No.: 25122-46-7
Compound CID: 32798
Formula: C25H32ClFO5
Formula Weight: 466.97

Specification

Stability: 3 years in powder form.
Storage: Storage at -20°C.
Applications: Clobetasol propionate is used in dermatological studies as a high-potency corticosteroid to investigate the management of resistant skin conditions and the suppression of local immune signaling.

Library Information

Target: Glucocorticoid receptor
Pathways: Endocrinology & Hormones
Plate Number: L6700-04
Empty Location: a1-h1; a12-h12
Container: 96-well plate
Formulation: 10mM DMSO
DMSO Max Solubility: 93 mg/mL; 199.16 mM
Ethanol Max Solubility: 20 mg/mL
ALogP: 3.958
HBA_Count: 4
HBD_Count: 1
Rotatable Bond: 5
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