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OSS_128167
Cat. No.:
OB0225WX-2769
Appearance:
Solid
Purity:
≥99%
Identity:
Confirmed by NMR, and HPLC.
Size:
Add to basket
Product Overview
Description:
OSS_128167 is a selective SIRT6 inhibitor with an IC50 of 89 micromolar, showing much lower potency against the SIRT1 and SIRT2 isoforms.
Synonym:
SIRT6-IN-1; 887686-02-4; OSS-128167; 5-(3-(Furan-2-carboxamido)benzamido)-2-hydroxybenzoic acid; 5-{3-[(Furan-2-carbonyl)-amino]-benzoylamino}-2-hydroxy-benzoic acid; 5-[3-(furan-2-amido)benzamido]-2-hydroxybenzoic acid; 5-[[3-(furan-2-carbonylamino)benzoyl]amino]-2-hydroxybenzoic acid; 5-[({3-[(furan-2-ylcarbonyl)amino]phenyl}carbonyl)amino]-2-hydroxybenzoic acid
CAS No.:
887686-02-4
Compound CID:
6496840
Formula:
C19H14N2O6
Formula Weight:
366.32
Specification
Stability:
3 years in powder form.
Storage:
Storage at -20°C.
Applications:
OSS_128167 is utilized in epigenetic research as a selective SIRT6 inhibitor to investigate the regulation of glucose metabolism and the modulation of DNA repair mechanisms.
Library Information
Target:
Sirtuin
Receptor:
SIRT1; SIRT2; SIRT6
Pathways:
Epigenetics
Plate Number:
L6700-10
Empty Location:
a1-h1; a12-h12
Container:
96-well plate
Formulation:
10mM DMSO
DMSO Max Solubility:
73 mg/mL; 199.28 mM
ALogP:
2.182
HBA_Count:
4
HBD_Count:
3
Rotatable Bond:
5
