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Gamma-Oryzanol
Cat. No.:
OB0225WX-2575
Appearance:
Solid
Purity:
≥96%
Identity:
Confirmed by NMR, and HPLC.
Size:
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Product Overview
Description:
Gamma-oryzanol is a bioactive phytochemical from rice bran oil that acts as a potent inhibitor of DNA methyltransferases, specifically targeting DNMT1 (IC50: 3.2 μM) and DNMT3a (IC50: 22.3 μM).
Synonym:
11042-64-1; Cycloartenyl ferulate; gamma Oryzanol; Gammariza; Oliver; gamma-Orizanol; HI-Z; Cycloartenol Trans-Ferulate; Cycloartenol ferulate; Oryzanol; Oryzanol A; 3-O-Ferulylcycloartenol; Ferulic acid cycloartenol ester; [(1S,3R,6S,8R,11S,12S,15R,16R)-7,7,12,16-tetramethyl-15-[(2R)-6-methylhept-5-en-2-yl]-6-pentacyclo[9.7.0.01,3.03,8.012,16]octadecanyl] (E)-3-(4-hydroxy-3-methoxyphenyl)prop-2-enoate; Cycloartenol ferulic acid ester; 9,19-Cyclolanost-24-en-3-ol, 3-[(2E)-3-(4-hydroxy-3-methoxyphenyl)-2-propenoate], (3.beta.)-; (3beta)-9,19-Cyclolanost-24-en-3-yl 4-hydroxy-3-methoxycinnamate
CAS No.:
11042-64-1
Compound CID:
5282164
Formula:
C40H58O4
Formula Weight:
602.89
Specification
Stability:
3 years in powder form.
Storage:
Storage at -20°C.
Applications:
Gamma-Oryzanol is employed in nutritional research as a mixture of ferulic acid esters to study its cholesterol-lowering effects and its impact on regulating autonomic nervous system function and oxidative balance.
Library Information
Target:
DNA methyltransferase
Receptor:
DNMT1
Pathways:
Epigenetics
Plate Number:
L6700-05
Empty Location:
a1-h1; a12-h12
Container:
96-well plate
Formulation:
10mM DMSO
DMSO Max Solubility:
100 mg/mL; 165.87 mM
ALogP:
9.806
HBA_Count:
3
HBD_Count:
1
Rotatable Bond:
9
