Selisistat (EX 527)

Cat. No.: OB0225WX-2424

Appearance: Solid

Purity: ≥99%

Identity: Confirmed by NMR, and HPLC.

Size:

INQUIRY Datasheet MSDS

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Product Overview

Description: Selisistat (EX 527) functions as a potent SIRT1 inhibitor with an IC50 of 38 nM, demonstrating over 200-fold selectivity compared to the SIRT2 and SIRT3 isoforms in biochemical assays.

Synonym: SEN0014196; 49843-98-3; Selisistat; 6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide; EX-527; EX 527; EX527; SIRT1 Inhibitor III; EX 527 (Selisistat); Selisistat (EX 527); rac-6-Chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide; MFCD03009471; 1H-Carbazole-1-carboxamide, 6-chloro-2,3,4,9-tetrahydro-; Cambridge id 6859180; (+/-)-6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide; 6-Chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxylic acid, amide

CAS No.: 49843-98-3

Compound CID: 5113032

Formula: C₁₃H₁₃ClN₂

Formula Weight: 248.71

Specification

Stability: 3 years in powder form.

Storage: Storage at -20°C.

Applications: Selisistat (EX 527) is applied in epigenetic research as a potent and selective SIRT1 inhibitor to investigate the role of sirtuin-mediated deacetylation in cellular aging, metabolism, and stress responses.