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ML347
Cat. No.:
OB0225LY-0188
Appearance:
Solid
Purity:
≥99%
Identity:
Confirmed by NMR, HPLC, and LC-MS.
Size:
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Product Overview
Description:
ML347 is a small molecule inhibitor that acts primarily on specific cell signaling pathways to regulate cell proliferation and survival.
Synonym:
LDN 193719; 1062368-49-3; 5-[6-(4-Methoxyphenyl)pyrazolo[1,5-a]pyrimidin-3-yl]quinoline; ML-347; 5-(6-(4-Methoxyphenyl)pyrazolo[1,5-a]pyrimidin-3-yl)quinoline; Quinoline, 5-[6-(4-methoxyphenyl)pyrazolo[1,5-a]pyrimidin-3-yl]-
CAS No.:
1062368-49-3
Compound CID:
44577753
Formula:
C22H16N4O
Formula Weight:
352.39
Specification
Targets&IC50:
ALK1: 46 nM; ALK2: 32 nM
Stability:
3 years in powder form.
Storage:
Storage at -20°C.
Applications:
ML347 can be used to study cell growth regulation mechanisms.
Library Information
Targets:
TGF-beta/Smad; ALK family
Receptors:
ALK1; ALK2; ALK3; ALK6; TGF-β receptor
Pathways:
Stem cells; Angiogenesis; Tyrosine kinase/adaptors
Plate Number:
AOCL-3
Plate Location:
d2
Empty Location:
a1-h1; a12-h12
Container:
96-well plate
Formulation:
10 mM DMSO
DMSO Max Solubility:
1 mg/ml
ALogP:
3.309
HBA_Count:
4
HBD_Count:
0
Rotatable Bond:
3
