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PF-04802367
Cat. No.:
OB0225WX-2157
Appearance:
Solid
Purity:
≥98%
Identity:
Confirmed by NMR, HPLC, and LC-MS.
Size:
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Product Overview
Description:
PF-04802367 is a highly potent GSK-3 inhibitor with IC50 values of 2.1 nM against recombinant human GSK-3β and approximately 10 nM for both isoforms in mobility shift assays.
Synonym:
1962178-27-3; 5-(3-Chloranyl-4-Methoxy-Phenyl)-~{n}-[3-(1,2,4-Triazol-1-Yl)propyl]-1,3-Oxazole-4-Carboxamide; N-(3-(1h-1,2,4-triazol-1-yl)propyl)-5-(3-chloro-4-methoxyphenyl)oxazole-4-carboxamide; 5-(3-chloro-4-methoxyphenyl)-N-[3-(1,2,4-triazol-1-yl)propyl]-1,3-oxazole-4-carboxamide
CAS No.:
1962178-27-3
Compound CID:
60148521
Formula:
C16H16ClN5O3
Formula Weight:
361.78
Specification
Targets&IC50:
GSK-3β: 9 nM (IC50); GSK-3α: 10 nM (IC50)
Stability:
3 years in powder form.
Storage:
Storage at -20°C.
Applications:
PF-04802367 is utilized in neurobiology research as a highly selective GSK-3 inhibitor to study the regulation of circadian rhythms and the modulation of behavioral responses in neurological models.
Library Information
Target:
GSK-3
Receptor:
GSK-3α; GSK-3β
Pathways:
Stem cells; PI3K/Akt/mTOR signaling
Plate Number:
AOCL-28
Plate Location:
f2
Empty Location:
a1-h1; a12-h12
Container:
96-well plate
Formulation:
10mM DMSO
DMSO Max Solubility:
100 mg/mL; 276.41 mM
