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Vitamin B12 test kit

Dorsomorphin

Cat. No.: OB0225LY-0195
Appearance: Solid
Purity: ≥99%
Identity: Confirmed by NMR, HPLC, and LC-MS.
Size:
Dorsomorphin

Product Overview

Description: Dorsomorphin is a small molecule compound that acts primarily as an antagonist of the BMP (bone morphogenetic protein) signaling pathway. It affects cell proliferation and differentiation by inhibiting the Smad signaling pathway.
Synonym: BML-275; 866405-64-3; 6-(4-(2-(Piperidin-1-yl)ethoxy)phenyl)-3-(pyridin-4-yl)pyrazolo[1,5-a]pyrimidine; 4-(6-{4-[2-(Piperidin-1-yl)ethoxy]phenyl}pyrazolo[1,5-a]pyrimidin-3-yl)pyridine; 6-(4-(2-(1-Piperidinyl)ethoxy)phenyl)-3-(4-pyridinyl)pyrazolo(1,5-a)pyrimidine; 4-(6-(4-(2-(Piperidin-1-yl)ethoxy)phenyl)pyrazolo(1,5-a)pyrimidin-3-yl)pyridine; Pyrazolo(1,5-a)pyrimidine, 6-(4-(2-(1-piperidinyl)ethoxy)phenyl)-3-(4-pyridinyl)-
CAS No.: 866405-64-3
Compound CID: 11524144
Formula: C24H25N5O
Formula Weight: 399.49

Specification

Relative Density: 1.255 g/cm3
Stability: 3 years in powder form.
Storage: Storage at -20°C.
Applications: Dorsomorphin can be used to study the regulatory mechanisms of the BMP signaling pathway or play an important role in stem cell differentiation and bone regeneration studies.

Library Information

Targets: Autophagy; AMPK; TGF-beta/Smad
Receptors: ALK2; ALK3; ALK6
Pathways: Stem cells; PI3K/Akt/mTOR signaling; Chromatin/Epigenetic; Autophagy
Plate Number: AOCL-3
Plate Location: d9
Empty Location: a1-h1; a12-h12
Container: 96-well plate
Formulation: 2 mM DMSO
DMSO Max Solubility: 1.33 mg/mL; 3.34 mM
Solubility: 10% DMSO+90% Saline: 0.13 mg/mL (0.33 mM)
ALogP: 3.028
HBA_Count: 4
HBD_Count: 0
Rotatable Bond: 6
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