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Galunisertib
Cat. No.:
OB0225LY-0217
Appearance:
Solid
Purity:
≥99%
Identity:
Confirmed by NMR and HPLC.
Size:
Product Overview
Description:
Galunisertib is a small molecule compound used to inhibit specific signaling pathways.
Synonym:
LY2157299; 700874-72-2; LY 2157299; LY-2157299; 4-(2-(6-Methylpyridin-2-yl)-5,6-dihydro-4H-pyrrolo[1,2-b]pyrazol-3-yl)quinoline-6-carboxamide; 4-[2-(6-Methylpyridin-2-yl)-5,6-dihydro-4H-pyrrolo[1,2-b]pyrazol-3-yl]quinoline-6-carboxamide; 4-[2-(6-Methyl-pyridin-2-yl)-5,6-dihydro-4H-pyrrolo[1,2-b]pyrazol-3-yl]-quinoline-6-carboxylic acid amide
CAS No.:
700874-72-2
Compound CID:
10090485
Formula:
C22H19N5O
Formula Weight:
369.42
Specification
Relative Density:
1.40 g/cm3
Stability:
3 years in powder form.
Storage:
Storage at -20°C.
Applications:
Galunisertib can be used in cell signaling regulation studies or play an important role in cancer biology research.
Library Information
Targets:
TGF-beta/Smad
Receptors:
TGF-β receptor; TβRI
Pathways:
Stem cells
Plate Number:
AOCL-3
Plate Location:
f11
Empty Location:
a1-h1; a12-h12
Container:
96-well plate
Formulation:
10 mM DMSO
DMSO Max Solubility:
50 mg/mL; 135.35 mM
Solubility:
10% DMSO+40% PEG300+5% Tween 80+45% Saline: 6.9 mg/mL (18.68 mM), insoluble in ethanol.
ALogP:
3.095
HBA_Count:
4
HBD_Count:
1
Rotatable Bond:
3
