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MGCD-265 analog
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Cat. No.:
OB0125LY-083
Size:
2 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg
CAS No.:
875337-44-3
Compound CID:
24901704
Specification
Description:
MGCD-265 analog is a multitargeted tyrosine kinase inhibitor that inhibits the activity of multiple receptor tyrosine kinases (RTKs).
Formula Weight:
517.6
Stability:
3 years in powder form.
Applications:
MGCD-265 analog has potential anti-tumor activity that can be used in cancer research.
Storage:
Storage at -20°C.
Formula:
C26H20FN5O2S2
Appearance:
Solid
Purity:
98.6%
Identity:
Confirmed by NMR, HPLC, and LC-MS.
Targets&IC50:
c-Met: 29 nM; VEGFR2: 10 nM
Relative Density:
1.41 g/cm3
Library Information
Plate Number:
AOCL-26
Plate Location:
b10
Empty Location:
a1-h1; a12-h12
Formulation:
10mM DMSO
Container:
96-well plate
Pathways:
Apoptosis; Angiogenesis; Tyrosine kinase/adaptors
Targets:
Apoptosis; VEGFR; c-Met/HGFR
Receptors:
Apoptosis; c-Met/HGFR; Met; RON; VEGFR; VEGFR1; VEGFR2; VEGFR3
DMSO Max Solubility (mg/mL):
96 mg/mL
DMSO Max Solubility (mM):
185.5 mM
Water Max Solubility (mg/mL):
1 mg/mL
Ethanol Max Solubility (mg/mL):
1 mg/mL
ALogP:
6.037
HBA_Count:
4
HBD_Count:
2
Rotatable Bond:
8