ML385

Cat. No.: 0225LY-1430

Appearance: Solid

Purity: ≥99%

Identity: Confirmed by NMR, HPLC, and LC-MS.

Size:

INQUIRY Datasheet MSDS

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Product Overview

Description: ML385 is a specific and novel inhibitor of NRF2 (IC50 = 1.9 uM) that provides anti-tumor and anti-inflammatory benefits by regulating oxidative stress pathways.

Synonym: 846557-71-9; ML-385; 2-(benzo[d][1,3]dioxol-5-yl)-N-(5-methyl-4-(1-(2-methylbenzoyl)indolin-5-yl)thiazol-2-yl)acetamide; 2-Benzo[1,3]dioxol-5-yl-N-{5-methyl-4-[1-(2-methyl-benzoyl)-2,3-dihydro-1H-indol-5-yl]-thiazol-2-yl}-acetamide; 2-(1,3-benzodioxol-5-yl)-N-[5-methyl-4-[1-(2-methylbenzoyl)-2,3-dihydroindol-5-yl]-1,3-thiazol-2-yl]acetamide; N-[4-[2,3-Dihydro-1-(2-methylbenzoyl)-1H-indol-5-yl]-5-methyl-2-thiazolyl]-1,3-benzodioxole-5-acetamide; 2-(2H-1,3-benzodioxol-5-yl)-N-{5-methyl-4-[1-(2-methylbenzoyl)-2,3-dihydro-1H-indol-5-yl]-1,3-thiazol-2-yl}acetamide

CAS No.: 846557-71-9

Compound CID: 1383822

Formula: C₂₉H₂₅N₃O₄S

Formula Weight: 511.59

Specification

Targets&IC50: Nrf2: 1.9 μM

Relative Density: 1.374 g/cm³

Stability: 3 years in powder form.

Storage: Storage at -20°C.

Applications: ML385 can be used in chemical biology to investigate the selective inhibition of the Nrf2-Keap1 interaction and its impact on antioxidant response.