Ki8751

Cat. No.: OB0225WX-2413

Appearance: Solid

Purity: ≥99%

Identity: Confirmed by NMR, and HPLC.

Size:

INQUIRY Datasheet MSDS

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Product Overview

Description: Ki8751 is a potent VEGFR2 inhibitor (IC50: 0.9 nM) that exhibits over 40-fold selectivity compared to c-Kit, PDGFR-alpha, and FGFR-2.

Synonym: 228559-41-9; Ki 8751; Ki-8751; N-(2,4-Difluorophenyl)-N'-[4-[(6,7-dimethoxy-4-quinolinyl)oxy]-2-fluorophenyl]urea; 1-(2,4-difluorophenyl)-3-(4-((6,7-dimethoxyquinolin-4-yl)oxy)-2-fluorophenyl)urea; 1-(2,4-difluorophenyl)-3-[4-(6,7-dimethoxyquinolin-4-yl)oxy-2-fluorophenyl]urea; 1-(2,4-Difluorophenyl)-3-(4-(6,7-dimethoxyquinolin-4-yl)oxy-2-fluorophenyl)urea; 1-(2,4-difluorophenyl)-3-{4-[(6,7-dimethoxyquinolin-4-yl)oxy]-2-fluorophenyl}urea; N-(2,4-Difluorophenyl)-N'-(4-((6,7-dimethoxy-4-quinolinyl)oxy)-2-fluorophenyl)urea; Urea, N-(2,4-difluorophenyl)-N'-(4-((6,7-dimethoxy-4-quinolinyl)oxy)-2-fluorophenyl)-; MFCD09971092; 1-(2,4-difluorophenyl)-3-(4-(6,7-dimethoxyquinolin-4-yloxy)-2-fluorophenyl)urea; 1-(2,4-Difluoro-phenyl)-3-[4-(6,7-dimethoxy-quinolin-4-yloxy)-2-fluoro-phenyl]-urea; 1-(2,4-difluorophenyl)-3-[4-[(6,7-dimethoxy-4-quinolinyl)oxy]-2-fluorophenyl]urea; N-(2,4-difluorophenyl)-N'-(4-((6,7-dimethoxy-4-quinolyl)oxy)-2-fluorophenyl)urea

CAS No.: 228559-41-9

Compound CID: 11317348

Formula: C₂₄H₁₈F₃N₃O₄

Formula Weight: 469.41

Specification

Stability: 3 years in powder form.

Storage: Storage at -20°C.

Applications: Ki8751 is employed in oncology research as a potent and selective VEGFR2 tyrosine kinase inhibitor to investigate the suppression of tumor-induced angiogenesis and the disruption of vascular signaling.