ZM 323881 HCl

Cat. No.: OB0225WX-2536

Appearance: Solid

Purity: ≥99%

Identity: Confirmed by NMR, and HPLC.

Size:

INQUIRY Datasheet MSDS

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Product Overview

Description: ZM 323881 is a potent VEGFR2 antagonist with an IC50 of less than 2 nM, showing nearly no inhibitory effect on VEGFR1, PDGFR-beta, or EGFR.

Synonym: 193000-39-4; ZM 323881 hydrochloride; ZM323881 hydrochloride; ZM323881 (hydrochloride); ZM-323881 hydrochloride; 4-fluoro-2-methyl-5-[(7-phenylmethoxyquinazolin-4-yl)amino]phenol;hydrochloride; 5-{[7-(benzyloxy)quinazolin-4-yl]amino}-4-fluoro-2-methylphenol hydrochloride; 5-((7-(benzyloxy)quinazolin-4-yl)amino)-4-fluoro-2-methylphenol hydrochloride; ZM323881 HCl; 5-[(7-Benzyloxyquinazolin-4-yl)amino]-4-fluoro-2-methylphenol hydrochloride; MFCD08703130; ZM 323881 monohydrochloride; ZM-323881 monohydrochloride; 7-benzyloxy-4-(2-fluoro-5-hydroxy-4-methylanilino)quinazoline hydrochloride; 4-Fluoro-2-methyl-5-[[7-(phenylmethoxy)-4-quinazolinyl]amino]phenol Hydrochloride; 5-((7-Benzyloxyquinazolin-4-yl )amino)-4-fluoro-2-methylphenol hydrochloride; 5-{[7-(Benzyloxy)-4-quinazolinyl]amino}-4-fluoro-2-methylphenol hydrochloride (1:1); 7-(benzyloxy)-N-(2-fluoro-5-hydroxy-4-methylphenyl)quinazolin-4-aminium chloride

CAS No.: 193000-39-4

Compound CID: 22624897

Formula: C₂₂H₁₈FN₃O₂·HCl

Formula Weight: 411.86

Specification

Stability: 3 years in powder form.

Storage: Storage at -20°C.

Applications: ZM 323881 HCl is applied in vascular biology as a potent and selective VEGFR2 inhibitor to investigate the molecular mechanisms of endothelial cell signaling and the inhibition of angiogenesis.