Products
Online Inquiry
WHI-P180
Cat. No.:
OB0225WX-2658
Appearance:
Solid
Purity:
≥99%
Identity:
Confirmed by NMR, and HPLC.
Size:
Add to basket
Product Overview
Description:
WHI-P180 is a multi-kinase antagonist with inhibitory concentrations (IC50) of 4.5 nM for the RET proto-oncogene and 66 nM for the kinase insert domain receptor (KDR).
Synonym:
211555-08-7
CAS No.:
211555-08-7
Formula:
C16H15N3O3
Formula Weight:
297.31
Specification
Stability:
3 years in powder form.
Storage:
Storage at -20°C.
Applications:
WHI-P180 is used in signal transduction research as a potent JAK3 inhibitor to investigate the regulation of immune cell signaling and the development of targeted therapies for leukemia.
Library Information
Target:
c-RET; VEGFR
Receptor:
c-RET; VEGFR
Pathways:
Protein tyrosine kinase
Plate Number:
L6700-07
Empty Location:
a1-h1; a12-h12
Container:
96-well plate
Formulation:
10mM DMSO
DMSO Max Solubility:
59 mg/mL; 198.45 mM
ALogP:
3.202
HBA_Count:
4
HBD_Count:
2
Rotatable Bond:
4
