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Harmine
Cat. No.:
OB0225WX-1732
Appearance:
Solid
Purity:
≥99%
Identity:
Confirmed by NMR, and HPLC.
Size:
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Product Overview
Description:
Harmine is a naturally occurring tricyclic beta-carboline alkaloid primarily isolated from the seeds of the Peganum harmala plant.
Synonym:
Telepathine; 442-51-3; 7-Methoxy-1-methyl-9H-pyrido[3,4-b]indole; Banisterine; Leucoharmine; Yageine; Yajeine; 9H-Pyrido[3,4-b]indole, 7-methoxy-1-methyl-; 7-Methoxy-1-methyl-9H-beta-carboline; Banisterin; Telepathin; Harmin; Yagein; 7-Methoxy-1-methyl-9H-pyrido(3,4-b)indole; 1-Methyl-7-methoxy-beta-carboline; Harmine (Telepathine); MFCD00004958; Harmin hydrochloride; 9H-Pyrido(3,4-b)indole, 7-methoxy-1-methyl-; BRN 0178813; 1-Methyl-7-methoxy-.beta.-carboline; Telepathien
CAS No.:
442-51-3
Compound CID:
5280953
Formula:
C13H12N2
Formula Weight:
212.25
Specification
Targets&IC50:
MAO-A: 0.048 μM(Ki)
Relative Density:
1.252 g/cm3
Stability:
3 years in powder form.
Storage:
Storage at -20°C.
Applications:
Harmine is applied in neuropharmacology and oncology research as a potent DYRK1A inhibitor to study its effects on neuronal differentiation, tau phosphorylation, and tumor cell proliferation.
Library Information
Target:
MAO; DYRK; 5-HT receptor
Receptor:
MAO; DYRK; 5-HT receptor
Pathways:
Tyrosine kinase/adaptors; Neuronal signaling; Cell cycle/Checkpoint; GPCR/G protein signaling; Metabolism
Plate Number:
AOCL-23
Plate Location:
b7
Empty Location:
a1-h1; a12-h12
Container:
96-well plate
Formulation:
10mM DMSO
DMSO Max Solubility:
3.85 mg/mL; 18.12 mM
ALogP:
2.438
HBA_Count:
2
HBD_Count:
1
Rotatable Bond:
1
