Brivanib (BMS-540215)

Cat. No.: OB0225WX-2390

Appearance: Solid

Purity: ≥99%

Identity: Confirmed by NMR, and HPLC.

Size:

INQUIRY Datasheet MSDS

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Product Overview

Description: Brivanib (BMS-540215) is an ATP-competitive small molecule that selectively inhibits VEGFR2 (IC50: 25 nM) while exhibiting moderate potency toward VEGFR-1 and FGFR-1.

Synonym: 649735-46-6; Brivanib; Brivanib (BMS-540215); BMS-540215; BMS 540215; BMS540215; (2R)-1-({4-[(4-fluoro-2-methyl-1H-indol-5-yl)oxy]-5-methylpyrrolo[2,1-f][1,2,4]triazin-6-yl}oxy)propan-2-ol; 1-[[4-[(4-fluoro-2-methyl-1H-indol-5-yl)oxy]-5-methylpyrrolo[2,1-f][1,2,4]triazin-6-yl]oxy]-2-propanol; (2R)-1-[4-[(4-fluoro-2-methyl-1H-indol-5-yl)oxy]-5-methylpyrrolo[2,1-f][1,2,4]triazin-6-yl]oxypropan-2-ol; (R)-1-(4-(4-Fluoro-2-methyl-1H-indol-5-yloxy)-5-methylpyrrolo(2,1-f)(1,2,4)triazin-6-yloxy)propan-2-ol; (R)-1-(4-(4-fluoro-2-methyl-1H-indol-5-yloxy)-5-methylpyrrolo[2,1-f][1,2,4]triazin-6-yloxy)propan-2-ol; 2-Propanol, 1-((4-((4-fluoro-2-methyl-1H-indol-5-yl)oxy)-5-methylpyrrolo(2,1-f)(1,2,4)triazin-6-yl)oxy)-, (2R)-; (R)-1-(4-(4-fluoro-2-methyl-1H-indol-5-yloxy)-5-methylpyrrolo[1,2-f][1,2,4]triazin-6-yloxy)propan-2-ol

CAS No.: 649735-46-6

Compound CID: 11234052

Formula: C₁₉H₁₉FN₄O₃

Formula Weight: 370.38

Specification

Stability: 3 years in powder form.

Storage: Storage at -20°C.

Applications: Brivanib (BMS-540215) is applied in hepatology and oncology research as a dual VEGFR and FGFR inhibitor to examine the prevention of fibrotic progression and the inhibition of hepatocellular carcinoma growth.