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7,8-Dihydroxyflavone
Cat. No.:
OB0225WX-2751
Appearance:
Solid
Purity:
≥99%
Identity:
Confirmed by NMR, and HPLC.
Size:
Add to basket
Product Overview
Description:
7,8-Dihydroxyflavone acts as a selective small-molecule agonist of the TrkB receptor with a binding affinity (Kd) of approximately 320 nM, mimicking the activity of BDNF.
Synonym:
7,8-DHF; 38183-03-8; 7,8-dihydroxy-2-phenyl-4H-chromen-4-one; 7,8-Dihydroxyflavone hydrate; 4H-1-Benzopyran-4-one, 7,8-dihydroxy-2-phenyl-; 7,8-Dihydroxy-flavone; 7,8-dihydroxy-2-phenylchromen-4-one; 7,8-Dihydroxy-2-phenyl-chromen-4-one; 7,8-Dihydroxy-2-phenyl-4-benzopyrone; MFCD00006836; 7,8-Dihydroxy-2-phenyl-4H-1-benzopyran-4-one; 7,8-dihydroxy-2-phenylchromone; 7,8-bis(oxidanyl)-2-phenyl-chromen-4-one; 7,8-Dihydroxy-2-phenyl-4H-chromen-4-one; 7,8-Dihydroxy-2-phenyl-4H-1-benzopyran-4-one
CAS No.:
38183-03-8
Compound CID:
1880
Formula:
C15H10O4
Formula Weight:
254.24
Specification
Stability:
3 years in powder form.
Storage:
Storage at -20°C.
Applications:
7,8-Dihydroxyflavone is employed in neurobiology research as a potent and selective TrkB receptor agonist to study its neuroprotective effects and its ability to mimic the activity of brain-derived neurotrophic factor (BDNF).
Library Information
Target:
Trk receptor
Receptor:
Trk receptor
Pathways:
Protein tyrosine kinase
Plate Number:
L6700-10
Empty Location:
a1-h1; a12-h12
Container:
96-well plate
Formulation:
10mM DMSO
DMSO Max Solubility:
50 mg/mL; 196.66 mM
Ethanol Max Solubility:
1 mg/mL
ALogP:
2.652
HBA_Count:
2
HBD_Count:
2
Rotatable Bond:
1
