PP121

Cat. No.: OB0225WX-2502

Appearance: Solid

Purity: ≥99%

Identity: Confirmed by NMR, and HPLC.

Size:

INQUIRY Datasheet MSDS

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Product Overview

Description: PP-121 is a multi-targeted kinase inhibitor that suppresses PDGFR, Hck, mTOR, VEGFR2, Src, and Abl with IC50 values ranging from 2 nM to 18 nM, while also inhibiting DNA-PK (IC50: 60 nM).

Synonym: 1092788-83-4; 1-cyclopentyl-3-(1H-pyrrolo[2,3-b]pyridin-5-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine; PP-121; PP 121; 1-cyclopentyl-3-(1H-pyrrolo[2,3-b]pyridin-5-yl)pyrazolo[3,4-d]pyrimidin-4-amine; 1H-Pyrazolo[3,4-d]pyrimidin-4-amine, 1-cyclopentyl-3-(1H-pyrrolo[2,3-b]pyridin-5-yl)-; 1-Cyclopentyl-3-(1H-pyrrolo(2,3-b)pyridin-5-yl)-1H-pyrazolo(3,4-d)pyrimidin-4-amine; 1H-Pyrazolo(3,4-d)pyrimidin-4-amine, 1-cyclopentyl-3-(1H-pyrrolo(2,3-b)pyridin-5-yl)-; 1-cyclopentyl-3-{1H-pyrrolo[2,3-b]pyridin-5-yl}pyrazolo[3,4-d]pyrimidin-4-amine; 1-cyclopentyl-3-(1H-pyrrolo(2,3-b)pyridin-5-yl)pyrazolo(3,4-d)pyrimidin-4-amine

CAS No.: 1092788-83-4

Compound CID: 24905142

Formula: C₁₇H₁₇N₇

Formula Weight: 319.36

Specification

Stability: 3 years in powder form.

Storage: Storage at -20°C.

Applications: PP121 is applied in signal transduction research as a dual-target inhibitor of PI3K and various receptor tyrosine kinases to study the simultaneous blockage of parallel growth signaling pathways.