SU5402

Cat. No.: OB0225WX-2697

Appearance: Solid

Purity: ≥99%

Identity: Confirmed by NMR, and HPLC.

Size:

INQUIRY Datasheet MSDS

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Product Overview

Description: SU5402 is a multi-targeted receptor tyrosine kinase inhibitor with IC50 values of 20 nM for VEGFR2, 30 nM for FGFR1, and 510 nM for PDGF-R-beta.

Synonym: 215543-92-3; su5402; SU 5402; SU-5402; 3-[4-methyl-2-[(Z)-(2-oxo-1H-indol-3-ylidene)methyl]-1H-pyrrol-3-yl]propanoic acid; 2-[(1,2-Dihydro-2-oxo-3H-indol-3-ylidene)methyl]-4-methyl-1H-pyrrole-3-propanoic acid; 3-[3-(2-Carboxyethyl)-4-methylpyrrol-2-methylidenyl]-2-indolinone; (Z)-3-(4-methyl-2-((2-oxoindolin-3-ylidene)methyl)-1H-pyrrol-3-yl)propanoic acid; 3-{[3-(2-carboxyethyl)-4-methylpyrrol-2-yl]methylene}-2-indolinone; (Z)-3-(4-Methyl-2-((2-oxoindolin-3-ylidene)-methyl)-1H-pyrrol-3-yl)propanoic acid; 3-{4-methyl-2-[(2-oxo-1,2-dihydro-3H-indol-3-ylidene)methyl]-1H-pyrrol-3-yl}propanoic acid; (Z)-3-[(3-(2-Carboxyethyl)-4-methylpyrrol-2-yl)methylidenyl]indolin-2-one; 2-[(1,2-Dihydro-2-oxo-3H-indol-3-yl idene)methyl]-4-methyl-1H-pyrrole-3-propanoic acid; 3-(4-methyl-2-((2-oxoindolin-3-ylidene)methyl)-1H-pyrrol-3-yl)propanoic acid; 3-(4-methyl-2-{[(3Z)-2-oxo-2,3-dihydro-1H-indol-3-ylidene]methyl}-1H-pyrrol-3-yl)propanoic acid; 3-{4-methyl-2-[(Z)-(2-oxo-1,2-dihydro-3H-indol-3-ylidene)methyl]-1H-pyrrol-3-yl}propanoic acid

CAS No.: 215543-92-3

Compound CID: 5289418

Formula: C₁₇H₁₆N₂O₃

Formula Weight: 296.32

Specification

Stability: 3 years in powder form.

Storage: Storage at -20°C.

Applications: SU5402 is utilized in developmental biology as a multi-target tyrosine kinase inhibitor to investigate the disruption of FGF, VEGF, and PDGF signaling during organogenesis and vascular development.