insulin (INS) CLIA kit

Cat. No.: 0126WXX-524

Assay Type: Quantitative CLIA

Assay Target: INS

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INQUIRY Datasheet MSDS

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Product Overview

Description: insulin (INS) CLIA kit is a CLIA-based in vitro research tool designed specifically for the quantitative detection of INS with a range of 39-2500 pg/mL and a minimum detectable dose (sensitivity) of <15 pg/mL. The kit is highly sensitive and easy to use.

Assay Principle: This sandwich CLIA Kit features a microtiter plate pre-coated with an INS-specific antibody. Standards or samples are incubated in the wells with a biotin-conjugated detection antibody, followed by the addition of avidin-HRP. A chemiluminescent substrate is introduced to produce a glowing light signal, the intensity of which is directly proportional to the INS level in the sample.

Background: INS is a hormone composed of an A chain and a B chain linked by two disulfide bonds. Secreted by the pancreas, it functions as a key regulator of metabolism within the body. Its primary role is to lower blood glucose levels by promoting glucose uptake into cells. INS is fundamentally linked to obesity through its role in energy metabolism and its relationship with insulin resistance. By targeting the insulin receptor signaling pathway and the diverse metabolic processes it regulates, researchers can develop novel anti-obesity therapies.

Synonyms: Pancreatic insulin

Applications: insulin (INS) CLIA kit is used to quantify INS in serum, plasma, and other biological fluids of , providing data to support research in a wide range of areas, including metabolic pathway, endocrinology, hormone metabolism, obesity, etc.

Research Area: Metabolic pathway; Endocrinology; Hormone metabolism; Obesity