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IMD 0354
Cat. No.:
OB0225WX-2530
Appearance:
Solid
Purity:
≥99%
Identity:
Confirmed by NMR, and HPLC.
Size:
Add to basket
Product Overview
Description:
IMD-0354 functions as a specific IKK-beta inhibitor that effectively prevents the phosphorylation of I-kappa-B-alpha within the NF-kappaB signaling cascade.
Synonym:
IKK2 Inhibitor V; 978-62-1; IMD-0354; N-(3,5-bis(trifluoromethyl)phenyl)-5-chloro-2-hydroxybenzamide; IKK-2 Inhibitor V; N-[3,5-bis(trifluoromethyl)phenyl]-5-chloro-2-hydroxybenzamide; IMD0354; MFCD00218820; Benzamide, N-(3,5-bis(trifluoromethyl)phenyl)-5-chloro-2-hydroxy-; 3',5'-Salicyloxylidide, 5-chloro-alpha,alpha,alpha,alpha',alpha',alpha'-hexafluoro-; N-[3,5-bis(trifluoromethyl)phenyl]-5-chloro-2-hydroxy-benzamide; N-(3,5-Bis-trifluoromethylphenyl)-5-chloro-2-hydroxybenzamide; IMD 0354; 5-Chloro-a,a,a,a',a',a'-hexafluoro-3',5'-salicyloxylidide N-(3,5-Bis(trifluoromethyl)phenyl)-5-chloro-2-hydroxybenzamide; IKK-2-inhibitor-V; 5-Chloro-2-hydroxy-N-[3,5-bis(trifluoromethyl)phenyl]benzamide; 5-chloro-2-hydroxy-N-[3,5-bis(trifluoromethyl)phenyl]-benzamide; 634914-41-3
CAS No.:
978-62-1
Compound CID:
5081913
Formula:
C15H8ClF6NO2
Formula Weight:
383.67
Specification
Stability:
3 years in powder form.
Storage:
Storage at -20°C.
Applications:
IMD 0354 is applied in molecular biology research as a selective IKK-beta inhibitor to study the prevention of p65 translocation and the suppression of NF-kappaB-driven gene expression.
Library Information
Target:
IκB/IKK
Receptor:
IKKβ
Pathways:
NF-κB
Plate Number:
L6700-04
Empty Location:
a1-h1; a12-h12
Container:
96-well plate
Formulation:
10mM DMSO
DMSO Max Solubility:
10 mg/mL; 26.06 mM
Ethanol Max Solubility:
77 mg/mL
ALogP:
4.921
HBA_Count:
1
HBD_Count:
2
Rotatable Bond:
4
