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Dehydrocostus lactone

Cat. No.: OB0225WX-2173
Appearance: Solid
Purity: ≥99%
Identity: Confirmed by NMR, and LC-MS.
Size:
Dehydrocostus lactone
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Product Overview

Description: Dehydrocostus lactone is a sesquiterpene lactone that exhibits a broad spectrum of biological properties, including immunomodulatory, anti-ulcer, and anti-tumor activities.
Synonym: Epiligulyl oxide; (-)-Dehydrocostus lactone; 477-43-0; Dehydrocostuslactone; Epiligulyl oxide; (-)-dehydrocostus lactone; (-)-dehydrocostuslactone; Azuleno[4,5-b]furan-2(3H)-one,decahydro-3,6,9-tris(methylene)-; (3aS,6aR,9aR,9bS)-3,6,9-trimethylenedecahydroazuleno[4,5-b]furan-2(3H)-one; (3aS,6aR,9aR,9bS)-decahydro-3,6,9-tris(methylene)azuleno[4,5-b]furan-2(3H)-one; (3aS,6aR,9aR,9bS)-3,6,9-trimethylidene-3a,4,5,6a,7,8,9a,9b-octahydroazuleno[4,5-b]furan-2-one; (3aR,6aS,9aS,9bR)-3,6,9-tris(methylidene)octahydroazuleno[4,5-b]furan-2,8(3H,4H)-dione; (3aS,6aR,9aR,9bS)-3,6,9-Trimethylenedecahydroazuleno[4,5-b]furan-2(9bH)-one; Guaia-4(15),10(14),11(13)-trien-12-oic acid, 6alpha-hydroxy-, gamma-lactone
CAS No.: 477-43-0
Compound CID: 73174
Formula: C15H18O2
Formula Weight: 230.3

Specification

Relative Density: 1.09 g/cm3
Stability: 3 years in powder form.
Storage: Storage at -20°C.
Applications: Dehydrocostus lactone is employed in pharmacological studies as a natural sesquiterpene lactone to investigate its anti-inflammatory effects and its ability to induce apoptosis in malignant cells via the inhibition of NF-kappaB.

Library Information

Target: IκB/IKK
Receptor: IKKβ
Pathways: NF-κB
Plate Number: AOCL-28
Plate Location: g8
Empty Location: a1-h1; a12-h12
Container: 96-well plate
Formulation: 10mM DMSO
DMSO Max Solubility: 60 mg/mL; 260.52 mM
ALogP: 3.282
HBA_Count: 2
HBD_Count: 0
Rotatable Bond: 0
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