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PS-1145
Cat. No.:
OB0225WX-2700
Appearance:
Solid
Purity:
≥99%
Identity:
Confirmed by NMR, and HPLC.
Size:
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Product Overview
Description:
PS-1145 is a highly specific inhibitor of the I-kappa-B kinase (IKK) complex, exhibiting an IC50 of 88 nM.
Synonym:
431898-65-6
CAS No.:
431898-65-6
Formula:
C17H11ClN4
Formula Weight:
322.75
Specification
Stability:
3 years in powder form.
Storage:
Storage at -20°C.
Applications:
PS-1145 is used in signal transduction research as a potent and selective IKK-beta inhibitor to investigate the suppression of TNF-alpha-induced NF-kappaB activation and the regulation of cell survival.
Library Information
Target:
IκB/IKK
Receptor:
IKK
Pathways:
NF-κB
Plate Number:
L6700-09
Empty Location:
a1-h1; a12-h12
Container:
96-well plate
Formulation:
10mM DMSO
DMSO Max Solubility:
64 mg/mL; 198.3 mM
Ethanol Max Solubility:
2 mg/mL
ALogP:
2.471
HBA_Count:
3
HBD_Count:
2
Rotatable Bond:
2
