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JSH-23
Cat. No.:
OB0225WX-2681
Appearance:
Solid
Purity:
≥99%
Identity:
Confirmed by NMR, and HPLC.
Size:
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Product Overview
Description:
JSH-23 acts as a small molecule inhibitor that targets NF-kappaB transcriptional activity, demonstrating an IC50 of 7.1 micromolar in the RAW 264.7 cell line.
Synonym:
749886-87-1; 4-Methyl-N1-(3-phenylpropyl)benzene-1,2-diamine; JSH 23; 4-Methyl-1-N-(3-phenylpropyl)benzene-1,2-diamine; NF-kappaB activation inhibitor II; MFCD09753595; JSH23; NFKB-activation-inhibitor-II; 4-Methyl-N~1~-(3-phenylpropyl)benzene-1,2-diamine; 4-Methyl-N1-(3-phenylpropyl)-1,2-phenylenediamine; 4-methyl-n1-(3-phenyl-propyl)-benzene-1,2-diamine; 4-methyl-N(1)-(3-phenylpropyl)benzene-1,2-diamine
CAS No.:
749886-87-1
Compound CID:
16760588
Formula:
C16H20N2
Formula Weight:
240.34
Specification
Stability:
3 years in powder form.
Storage:
Storage at -20°C.
Applications:
JSH-23 is utilized in signal transduction research as a specialized chemical tool to investigate the inhibition of NF-kappaB transcriptional activity and the regulation of nuclear translocation in inflammatory cell models.
Library Information
Target:
NF-κB
Receptor:
NF-κB
Pathways:
NF-κB
Plate Number:
L6700-08
Empty Location:
a1-h1; a12-h12
Container:
96-well plate
Formulation:
10mM DMSO
DMSO Max Solubility:
48 mg/mL; 199.72 mM
Ethanol Max Solubility:
16 mg/mL
ALogP:
3.739
HBA_Count:
0
HBD_Count:
2
Rotatable Bond:
5
