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Pyrrolidinedithiocarbamate ammonium
Cat. No.:
OB0225WX-2554
Appearance:
Solid
Purity:
≥99%
Identity:
Confirmed by NMR, and HPLC.
Size:
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Product Overview
Description:
Pyrrolidinedithiocarbamate ammonium is a robust inhibitor of the nuclear factor-κB (NF-κB) pathway that acts by preventing IκB phosphorylation and blocking the nuclear translocation of NF-κB.
Synonym:
APDC; PDTC; Pyrrolidine dithiocarbamic acid ammonium salt; 5108-96-3; Pyrrolidine-1-carbodithioic acid; Pyrrolidine dithiocarbamic acid; Pyrrolidine dithiocarbamate; 1-Pyrrolidinecarbodithioic acid; PDTC; Pyrrolidinedithiocarbamate; Pyrrolidine-N-carbodithioic acid; apdc; Tetramethylenedithiocarbamic acid; Ammonium pyrrolidine dithiocarbamate; 1-Pyrrolidinecarbodithioic acid, ammonium salt; Ammonium 1-pyrrolidinecarbodithioate; Pyrrolidine-N-dithiocarbamic acid ammonium salt
CAS No.:
5108-96-3
Compound CID:
65351
Formula:
C5H9NS2·H3
Formula Weight:
164.29
Specification
Stability:
3 years in powder form.
Storage:
Storage at -20°C.
Applications:
Pyrrolidinedithiocarbamate ammonium is used in molecular biology as a potent inhibitor of NF-kappaB and a metal chelator to investigate the regulation of redox-sensitive gene expression and cellular antioxidant responses.
Library Information
Target:
NF-κB
Receptor:
NF-κB
Pathways:
NF-κB
Plate Number:
L6700-05
Empty Location:
a1-h1; a12-h12
Container:
96-well plate
Formulation:
10mM DMSO
DMSO Max Solubility:
32 mg/mL; 194.78 mM
Water Max Solubility:
32 mg/mL; 194.78 mM
ALogP:
2.172
HBA_Count:
0
HBD_Count:
0
Rotatable Bond:
1
