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Kukoamine A
Cat. No.:
0225LY-0708
Appearance:
Solid
Purity:
≥99%
Identity:
Confirmed by HPLC.
Size:
Add to basket
Product Overview
Description:
Kukoamine A is a mixed inhibitor of trypanothione reductase (Ki = 1.8 micromolar) that provides antioxidant, cytoprotective, anti-inflammatory, and anticancer benefits.
Synonym:
75288-96-9; 3-(3,4-dihydroxyphenyl)-N-[3-[4-[3-[3-(3,4-dihydroxyphenyl)propanoylamino]propylamino]butylamino]propyl]propanamide; N1,N2-bis(dihydrocaffeoyl)spermine; 1,14-Bis(dihydrocaffeoyl)spermine; N1,N12-Bis(dihydrocaffeoyl) spermine; ZINC-13513540; Benzenepropanamide, N,N'-[1,4-butanediylbis(imino-3,1-propanediyl)]bis[3,4-dihydroxy-; N,N'-[1,4-butanediylbis(imino-3,1-propanediyl)]bis[3,4-dihydroxybenzenepropanamide]; 3-(3,4-Bis(oxidanyl)phenyl)-N-(3-(4-(3-(3-(3,4-bis(oxidanyl)phenyl)propanoylamino)propylamino)butylamino)propyl)propanamide; 3-(3,4-Dihydroxy-phenyl)-N-[3-(4-{3-[3-(3,4-dihydroxy-phenyl)-propionylamino]-propylamino}-butylamino)-propyl]-propionamide
CAS No.:
75288-96-9
Compound CID:
5318865
Formula:
C28H42N4O6
Formula Weight:
530.66
Specification
Targets&IC50:
LOX: 9.5 microM; Trypanothione reductase: 1.8 microM(Ki)
Relative Density:
1.213 g/cm3 at 20°C.
Stability:
3 years in powder form.
Storage:
Storage at -20°C.
Applications:
Kukoamine A can be used in neuroscience research to study its antioxidant and anti-inflammatory effects in protecting against neurotoxicity.
Library Information
Target:
Parasite protein; NF-κB; DNA/RNA synthesis; Lipoxygenase
Receptor:
AP-1; LOX; NF-κB; Parasite protein
Pathways:
NF-κB; DNA damage/DNA repair; Cell cycle/Checkpoint; Metabolism; Microbiology/Virology
Plate Number:
AOCL-10
Plate Location:
b5
Empty Location:
a1-h1; a12-h12
Container:
96-well plate
Formulation:
10mM DMSO
DMSO Max Solubility:
60 mg/mL; 113.07 mM
Water Max Solubility:
100 mg/mL; 188.44 mM





